M
Michel Bouvier
Researcher at Université de Montréal
Publications - 412
Citations - 33931
Michel Bouvier is an academic researcher from Université de Montréal. The author has contributed to research in topics: Receptor & G protein-coupled receptor. The author has an hindex of 97, co-authored 396 publications receiving 31267 citations. Previous affiliations of Michel Bouvier include École Polytechnique de Montréal & University of Catania.
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Journal ArticleDOI
Free and Conjugated Catecholamines in Plasma and Red Blood Cells of Normotensive and Hypertensive Patients
TL;DR: Various abnormalities in the metabolism of CA in hypertensive patients could contribute to the maintenance of hypertension by an alteration of the biological expression of the sympathetic tone at the cellular level of these patients.
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Circadian, Sleep and Caloric Intake Phenotyping in Type 2 Diabetes Patients With Rare Melatonin Receptor 2 Mutations and Controls: A Pilot Study.
Akram Imam,Eva C. Winnebeck,Nina Buchholz,Philippe Froguel,Philippe Froguel,Amélie Bonnefond,Amélie Bonnefond,Michele Solimena,Anna Ivanova,Michel Bouvier,Bianca Plouffe,Bianca Plouffe,Guillaume Charpentier,Angeliki Karamitri,Ralf Jockers,Till Roenneberg,Céline Vetter,Céline Vetter +17 more
TL;DR: Compared to diabetic controls, T2D MT2 patients display a number of adverse sleep, circadian, and caloric intake phenotypes, including more irregular behavioral timing, which is suggested to be associated with type 2 diabetes onset and severity.
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Effects of morphine on electrical activity of the rectum in man.
TL;DR: Morphine failed to activate an aganglionic rectum in a patient with Hirschsprung's disease, indicating that it had no direct effect on smooth muscle cells, and it is therefore probable that morphine may have an effect on the intrinsic innervation.
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Hybridization of β-Adrenergic Agonists and Antagonists Confers G Protein Bias
Markus Stanek,Louis-Philippe Picard,Maximilian F. Schmidt,Jonas Kaindl,Harald Hübner,Michel Bouvier,Dorothee Weikert,Peter Gmeiner +7 more
TL;DR: Molecular dynamics simulations suggest that the difference in G protein efficacy and β-arrestin recruitment of the hybrid ( S)-22, the full agonist epinephrine, and the β2-selective, G protein-biased partial agonist salmeterol depends on specific hydrogen bonding between Ser5.46 and Asn6.55 and the aromatic head group of the ligands.
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Comparative binding study of rat natriuretic peptide receptor-A.
TL;DR: It appears that NPR-A alone can account for the two binding components found in the rat papillae and that a single molecular form of the protein is implicated.