Miquel Ràmia

TL;DR: The Drosophila melanogaster Genetic Reference Panel is described, a community resource for analysis of population genomics and quantitative traits, which reveals reduced polymorphism in centromeric autosomal regions and the X chromosomes, evidence for positive and negative selection, and rapid evolution of the X chromosome.

TL;DR: An integrated genotyping strategy was used to identify 4,853,802 single nucleotide polymorphisms (SNPs) and 1,296,080 non-SNP variants and identified 16 polymorphic inversions in the DGRP, finding variation in genome size and many quantitative traits are significantly associated with inversions.

TL;DR: Gene duplication analysis identified lineage-specific expanded families with functional annotations associated with proteolysis, zinc ion binding, chitin binding, sensory perception, ethanol tolerance, immunity, physiology, and reproduction that are promising candidates for explaining the adaptation of these species to their distinct ecological niches.

TL;DR: InvFEST aims to represent the most reliable set of human inversions and become a central repository to share information, guide future studies and contribute to the analysis of the functional and evolutionary impact of inversions on the human genome.

TL;DR: A new genome browser specially designed for the automatic analysis and representation of genetic variation across the D. melanogaster genome sequence, which allows estimating and visualizing the values of a number of DNA polymorphism and divergence summary statistics, linkage disequilibrium parameters and several neutrality tests.