David Castellano

TL;DR: The Drosophila melanogaster Genetic Reference Panel is described, a community resource for analysis of population genomics and quantitative traits, which reveals reduced polymorphism in centromeric autosomal regions and the X chromosomes, evidence for positive and negative selection, and rapid evolution of the X chromosome.

TL;DR: It is concluded that HRi hampers the rate of adaptive evolution in Drosophila and that the variation in recombination, mutation, and gene density along the genome affects the HRi effect.

TL;DR: The results indicate that the genome is more dynamic than previously thought and that human inversions have important functional and evolutionary consequences, making possible to determine for the first time their contribution to complex traits.

TL;DR: It is shown that the ratio of the number of nonsynonymous and synonymous polymorphisms is negatively correlated to the numberOf synonymous polymorphism, even when the nonindependence is accounted for, and this is consistent with a model of genetic hitchhiking: Genetic hitchh hiking depresses diversity at neutral and weakly selected sites, but has little effect on the diversity of strongly selected sites.

TL;DR: The method by which this relationship is examined is introduced, which shows that these two variables are strongly negatively and linearly correlated on a log scale, and that the slope of this relationship differs between the two phylogenetic groups for which the authors have the most data, rodents and bats.