D
Dianhui Zhu
Researcher at Baylor College of Medicine
Publications - 8
Citations - 3857
Dianhui Zhu is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Population & Quantitative trait locus. The author has an hindex of 8, co-authored 8 publications receiving 3460 citations. Previous affiliations of Dianhui Zhu include Human Genome Sequencing Center.
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Journal ArticleDOI
The Drosophila melanogaster Genetic Reference Panel
Trudy F. C. Mackay,Stephen Richards,Eric A. Stone,Antonio Barbadilla,Julien F. Ayroles,Julien F. Ayroles,Dianhui Zhu,Sònia Casillas,Yi Han,Michael M. Magwire,Julie M. Cridland,Mark F. Richardson,Robert R. H. Anholt,Maite G. Barrón,Crystal Bess,Kerstin P. Blankenburg,Mary Anna Carbone,David Castellano,Lesley S. Chaboub,Laura H Duncan,Zeke Harris,Mehwish Javaid,Joy Jayaseelan,Shalini N. Jhangiani,Katherine W. Jordan,Fremiet Lara,Faye Lawrence,Sandra L. Lee,Pablo Librado,Raquel S. Linheiro,Richard F. Lyman,Aaron J. Mackey,Mala Munidasa,Donna M. Muzny,Lynne V. Nazareth,Irene Newsham,Lora Perales,Ling-Ling Pu,Carson Qu,Miquel Ràmia,Jeffrey G. Reid,Stephanie M. Rollmann,Stephanie M. Rollmann,Julio Rozas,Nehad Saada,Lavanya Turlapati,Kim C. Worley,Yuanqing Wu,Akihiko Yamamoto,Yiming Zhu,Casey M. Bergman,Kevin R. Thornton,David Mittelman,Richard A. Gibbs +53 more
TL;DR: The Drosophila melanogaster Genetic Reference Panel is described, a community resource for analysis of population genomics and quantitative traits, which reveals reduced polymorphism in centromeric autosomal regions and the X chromosomes, evidence for positive and negative selection, and rapid evolution of the X chromosome.
Journal ArticleDOI
A Catalog of Reference Genomes from the Human Microbiome
Karen E. Nelson,George M. Weinstock,Sarah K. Highlander,Kim C. Worley,Heather Huot Creasy,Jennifer R. Wortman,Douglas B. Rusch,Makedonka Mitreva,Erica Sodergren,Asif T. Chinwalla,Michael Feldgarden,Dirk Gevers,Brian J. Haas,Ramana Madupu,Doyle V. Ward,Bruce W. Birren,Richard A. Gibbs,Barbara A. Methé,Joseph F. Petrosino,Robert L. Strausberg,Granger G. Sutton,Owen White,Richard K. Wilson,Scott Durkin,Michelle G. Giglio,Sharvari Gujja,Clint Howarth,Chinnappa D. Kodira,Nikos C. Kyrpides,Teena Mehta,Donna M. Muzny,Matthew D. Pearson,Kymberlie H. Pepin,Amrita Pati,Xiang Qin,Chandri N. Yandava,Qiandong Zeng,Lan Zhang,Aaron M. Berlin,Lei Chen,Theresa A. Hepburn,Justin Johnson,Jamison McCorrison,Jason R. Miller,Patrick Minx,Chad Nusbaum,Carsten Russ,Sean M. Sykes,Chad Tomlinson,Sarah Young,Wesley C. Warren,Jonathan H. Badger,Jonathan Crabtree,Victor Markowitz,Joshua Orvis,Andrew Cree,Steve Ferriera,Lucinda Fulton,Robert S. Fulton,Marcus Gillis,Lisa Hemphill,Vandita Joshi,Christie Kovar,Manolito Torralba,Kris A. Wetterstrand,Amr Abouellleil,Aye Wollam,Christian J. Buhay,Yan Ding,Shannon Dugan,Michael Fitzgerald,Mike Holder,Jessica B. Hostetler,Sandra W. Clifton,Emma Allen-Vercoe,Ashlee M. Earl,Candace N. Farmer,Konstantinos Liolios,Michael G. Surette,Qiang Xu,Craig Pohl,Katarzyna Wilczek-Boney,Dianhui Zhu +82 more
TL;DR: Results from an initial reference genome sequencing of 178 microbial genomes allow for ~40% of random sequences from the microbiome of the gastrointestinal tract to be associated with organisms based on the match criteria used, suggesting that the authors are still far from saturating microbial species genetic data sets.
Journal ArticleDOI
Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines
Wen Huang,Andreas Massouras,Andreas Massouras,Yutaka Inoue,Jason A. Peiffer,Miquel Ràmia,Aaron M. Tarone,Lavanya Turlapati,Thomas Zichner,Dianhui Zhu,Richard F. Lyman,Michael M. Magwire,Kerstin P. Blankenburg,Mary Anna Carbone,Kyle Chang,Lisa L. Ellis,Sonia Fernandez,Yi Han,Gareth Highnam,Carl E. Hjelmen,John Jack,Mehwish Javaid,Joy Jayaseelan,Divya Kalra,Sandy Lee,Lora Lewis,Mala Munidasa,Fiona Ongeri,Shohba Patel,Lora Perales,Agapito Perez,Ling-Ling Pu,Stephanie M. Rollmann,Robert Ruth,Nehad Saada,Crystal B. Warner,Aneisa Williams,Yuanqing Wu,Akihiko Yamamoto,Yiqing Zhang,Yiming Zhu,Robert R. H. Anholt,Jan O. Korbel,David Mittelman,Donna M. Muzny,Richard A. Gibbs,Antonio Barbadilla,J. Spencer Johnston,Eric A. Stone,Stephen Richards,Bart Deplancke,Bart Deplancke,Trudy F. C. Mackay +52 more
TL;DR: An integrated genotyping strategy was used to identify 4,853,802 single nucleotide polymorphisms (SNPs) and 1,296,080 non-SNP variants and identified 16 polymorphic inversions in the DGRP, finding variation in genome size and many quantitative traits are significantly associated with inversions.
Journal ArticleDOI
Finding the missing honey bee genes: Lessons learned from a genome upgrade
Christine G. Elsik,Christine G. Elsik,Kim C. Worley,Anna K. Bennett,Martin Beye,Francisco Camara,Christopher P. Childers,Christopher P. Childers,Dirk C. de Graaf,Griet Debyser,Jixin Deng,Bart Devreese,Eran Elhaik,Jay D. Evans,Leonard J. Foster,Dan Graur,Roderic Guigó,Katharina J. Hoff,Michael Holder,Matthew E. Hudson,Greg J. Hunt,Huaiyang Jiang,Vandita Joshi,Radhika S. Khetani,Peter Kosarev,Christie Kovar,Jian Ma,Ryszard Maleszka,Robin F. A. Moritz,Monica Munoz-Torres,Monica Munoz-Torres,Terence Murphy,Donna M. Muzny,Irene Newsham,Justin T. Reese,Justin T. Reese,Hugh M. Robertson,Gene E. Robinson,Olav Rueppell,Victor V. Solovyev,Mario Stanke,Eckart Stolle,Jennifer M. Tsuruda,Matthias Van Vaerenbergh,Robert M. Waterhouse,Daniel B. Weaver,Charles W. Whitfield,Yuanqing Wu,Evgeny M. Zdobnov,Lan Zhang,Dianhui Zhu,Richard A. Gibbs +51 more
TL;DR: Improved honey bee genome assembly with a new gene annotation set and a number of genes similar to that of other insect genomes are reported, contrary to what was suggested in OGSv1.0.
Journal ArticleDOI
Epistasis dominates the genetic architecture of Drosophila quantitative traits.
Wen Huang,Stephen Richards,Mary Anna Carbone,Dianhui Zhu,Robert R. H. Anholt,Julien F. Ayroles,Laura H Duncan,Katherine W. Jordan,Faye Lawrence,Michael M. Magwire,Crystal B. Warner,Kerstin P. Blankenburg,Yi Han,Mehwish Javaid,Joy Jayaseelan,Shalini N. Jhangiani,Donna M. Muzny,Fiona Ongeri,Lora Perales,Yuan Qing Wu,Yiqing Zhang,Xiaoyan Zou,Eric A. Stone,Richard A. Gibbs,Trudy F. C. Mackay +24 more
TL;DR: In this article, the authors compared the genetic architecture of three Drosophila life history traits in the sequenced inbred lines of the melanogaster Genetic Reference Panel (DGRP) and a large outbred, advanced intercross population derived from 40 DGRP lines (Flyland).