M
Monica Campbell
Researcher at University of Colorado Denver
Publications - 28
Citations - 997
Monica Campbell is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Population & Gene. The author has an hindex of 11, co-authored 27 publications receiving 782 citations. Previous affiliations of Monica Campbell include Johns Hopkins University & Johns Hopkins University School of Medicine.
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Journal ArticleDOI
Assembly of a pan-genome from deep sequencing of 910 humans of African descent
Rachel M. Sherman,Juliet Forman,Juliet Forman,Valentin Antonescu,Daniela Puiu,Michelle Daya,Nicholas Rafaels,Meher Preethi Boorgula,Sameer Chavan,Candelaria Vergara,Victor E. Ortega,Albert M. Levin,Celeste Eng,Maria Yazdanbakhsh,James G. Wilson,Javier Marrugo,Leslie A. Lange,L. Keoki Williams,Harold Watson,Lorraine B. Ware,Christopher O. Olopade,Olufunmilayo I. Olopade,Ricardo Riccio Oliveira,Carole Ober,Dan L. Nicolae,Deborah A. Meyers,Alvaro Mayorga,Jennifer Knight-Madden,Tina V. Hartert,Nadia N. Hansel,Marilyn G. Foreman,Jean G. Ford,Mezbah U. Faruque,Georgia M. Dunston,Luis Caraballo,Esteban G. Burchard,Eugene R. Bleecker,Maria Ilma Araujo,Edwin Francisco Herrera-Paz,Monica Campbell,Cassandra Foster,Margaret A. Taub,Terri H. Beaty,Ingo Ruczinski,Rasika A. Mathias,Kathleen C. Barnes,Steven L. Salzberg +46 more
TL;DR: A deeply sequenced dataset of 910 individuals, all of African descent, is used to construct a set of DNA sequences that is present in these individuals but missing from the reference human genome, demonstrating that the African pan-genome contains ~10% more DNA than the current human reference genome.
Journal ArticleDOI
A genome-wide association study on African-ancestry populations for asthma.
Rasika A. Mathias,Audrey V. Grant,Nicholas Rafaels,T. Hand,Li Gao,Candelaria Vergara,Yuhjung J. Tsai,Mao Yang,Monica Campbell,Cassandra Foster,Peisong Gao,Alkis Togias,Nadia N. Hansel,Gregory B. Diette,N. Franklin Adkinson,Mark C. Liu,Mezbah U. Faruque,Georgia M. Dunston,Harold Watson,Michael B. Bracken,Josephine Hoh,Pissamai Maul,Trevor Maul,Anne E. Jedlicka,Tanda Murray,Jacqueline B. Hetmanski,Roxann Ashworth,Chrissie M. Ongaco,Kurt N. Hetrick,Kimberly F. Doheny,Elizabeth W. Pugh,Charles N. Rotimi,Jean G. Ford,Celeste Eng,Esteban G. Burchard,Patrick M. A. Sleiman,Hakon Hakonarson,Erick Forno,Benjamin A. Raby,Scott T. Weiss,Alan F. Scott,Michael Kabesch,Liming Liang,Gonçalo R. Abecasis,Miriam F. Moffatt,William O.C.M. Cookson,Ingo Ruczinski,Terri H. Beaty,Kathleen C. Barnes +48 more
TL;DR: This study illustrates the complexity of identifying true associations for a complex and heterogeneous disease, such as asthma, in admixed populations, especially populations of African descent.
Journal ArticleDOI
FADS genetic variants and ω-6 polyunsaturated fatty acid metabolism in a homogeneous island population.
Rasika A. Mathias,Candelaria Vergara,Li Gao,Nicholas Rafaels,T. Hand,Monica Campbell,Carol A. Bickel,Priscilla Ivester,Susan Sergeant,Kathleen C. Barnes,Floyd H. Chilton +10 more
TL;DR: Findings in a geographically isolated population with a homogenous dietary environment suggest that variants in the Δ-5 desaturase enzymatic step likely regulate the efficiency of conversion of medium-chain PUFAs to potentially inflammatory PUFas, such as AA.
Journal ArticleDOI
African ancestry is associated with risk of asthma and high total serum IgE in a population from the Caribbean Coast of Colombia.
Candelaria Vergara,Luis Caraballo,Dilia Mercado,Silvia Jiménez,Winston Rojas,Nicholas Rafaels,T. Hand,Monica Campbell,Yuhjung J. Tsai,Li Gao,Constanza Duque,Sergio Lopez,Gabriel Bedoya,Andres Ruiz-Linares,Andres Ruiz-Linares,Kathleen C. Barnes +15 more
TL;DR: The findings indicate that genetic factors can explain the association between asthma and African ancestry and suggest that this sample is a useful resource for performing admixture mapping for asthma.
Journal ArticleDOI
Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations.
Michelle Daya,Nicholas Rafaels,Tonya M. Brunetti,Sameer Chavan,Albert M. Levin,Aniket Shetty,Christopher R. Gignoux,Meher Preethi Boorgula,Genevieve L. Wojcik,Monica Campbell,Candelaria Vergara,Dara G. Torgerson,Victor E. Ortega,Ayo P. Doumatey,Henry Richard Johnston,Nathalie Acevedo,Maria Ilma Araujo,Pedro C. Avila,Gillian M. Belbin,Eugene R. Bleecker,Carlos Bustamante,Luis Caraballo,Alvaro A. Cruz,Georgia M. Dunston,Celeste Eng,Mezbah U. Faruque,Trevor S. Ferguson,Camila Alexandrina Figueiredo,Jean G. Ford,Weiniu Gan,Pierre-Antoine Gourraud,Nadia N. Hansel,Ryan D. Hernandez,Edwin Francisco Herrera-Paz,Silvia Jiménez,Eimear E. Kenny,Jennifer Knight-Madden,Rajesh Kumar,Leslie A. Lange,Ethan M. Lange,Antoine Lizee,Pissamai Maul,Trevor Maul,Alvaro Mayorga,Deborah A. Meyers,Dan L. Nicolae,Timothy D. O’Connor,Ricardo Riccio Oliveira,Christopher O. Olopade,Olufunmilayo I. Olopade,Zhaohui S. Qin,Charles N. Rotimi,Nicolas Vince,Harold Watson,Rainford J. Wilks,James G. Wilson,Steven L. Salzberg,Carole Ober,Esteban G. Burchard,L. Keoki Williams,Terri H. Beaty,Margaret A. Taub,Ingo Ruczinski,Rasika A. Mathias,Kathleen C. Barnes,Caapa +65 more
TL;DR: A genome-wide meta-analysis from the Consortium on Asthma among African Ancestry Populations (CAAPA) finds strong evidence for association at four previously reported asthma loci and identifies two potentially African ancestry-specific loci that may be specific to asthma risk in African ancestry populations.