Oliver Schmutzler

TL;DR: X-ray-based analytics are routinely applied in many fields, including physics, chemistry, materials science, and engineering as discussed by the authors, but the full potential of such techniques in the life sciences and medicine has not yet been fully exploited.

TL;DR: Specific localisation to sites of disease is demonstrated by adapting gold-nanoparticles with small targeting ligands in murine spinal cord injury models, at record sensitivity levels using sub-mm resolution, which contribute to the future use of molecularly-targeted gold- nanoparticles as next-generation clinical diagnostic and pharmacokinetic tools.

TL;DR: In this article, the authors demonstrate the application of synchrotron-based X-ray fluorescence imaging (XFI) on prostate tumor cells, which have internalized differently functionalized gold nanoparticles.

TL;DR: In this article, the feasibility of X-ray fluorescence imaging (XFI) to track immune cells and thus monitor the immune response was evaluated using Monte Carlo simulations using a mouse voxel model, where spherical targets were positioned within the model and imaged using a monochromatic photon beam of 53 or 85 keV.

TL;DR: In this article , a synchrotron-based approach for reducing the minimal detectable marker concentration by demonstrating the feasibility of XFI for measuring the yet inaccessible distribution of the endogenous iodine in murine thyroids under in-vivo conform conditions.