O
Olivier Frey
Researcher at ETH Zurich
Publications - 69
Citations - 2454
Olivier Frey is an academic researcher from ETH Zurich. The author has contributed to research in topics: Biosensor & Microelectrode. The author has an hindex of 24, co-authored 66 publications receiving 1928 citations. Previous affiliations of Olivier Frey include Ludwig Maximilian University of Munich & Technische Universität München.
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Journal ArticleDOI
Reconfigurable microfluidic hanging drop network for multi-tissue interaction and analysis
TL;DR: A platform that extends the hanging-drop technology, used for multi-cellular spheroid formation, to multifunctional complex microfluidic networks, and is a promising technology for 'body-on-a-chip'-related research.
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Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing.
Uwe Marx,Tommy B. Andersson,Anthony Bahinski,Mario Beilmann,Sonja Beken,Flemming R. Cassee,Murat Cirit,Mardas Daneshian,Susan Fitzpatrick,Olivier Frey,Claudia Gaertner,Christoph Giese,Linda G. Griffith,Thomas Hartung,Minne B. Heringa,Julia Hoeng,Wim H. de Jong,Hajime Kojima,Jochen Kuehnl,Marcel Leist,Andreas Luch,Ilka Maschmeyer,D. A. Sakharov,Adriënne J.A.M. Sips,Thomas Steger-Hartmann,Danilo A. Tagle,Alexander G. Tonevitsky,Tewes Tralau,Sergej Tsyb,Anja van de Stolpe,Rob J. Vandebriel,Paul Vulto,Jufeng Wang,Joachim Wiest,Marleen Rodenburg,Adrian Roth +35 more
TL;DR: The status quo of microphysiological systems available today against industry needs is reviewed, and the broad variety of approaches with fit-for-purpose potential in the drug development cycle are assessed, and feasibility solutions to reach the next levels of human biology in vitro are proposed.
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Electrochemical comparison of IrO2 prepared by anodic oxidation of pure iridium and IrO2 prepared by thermal decomposition of H2IrCl6 precursor solution
TL;DR: In this article, surface redox activities, oxygen evolution reaction (OER), oxidation of formic acid (FA), and anodic stability were investigated and compared for IrO2 electrodes prepared by two techniques: the thermal decomposition of H2IrCl6 precursor (TDIROF) and the anodic oxidation of metallic iridium (AIROF).
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Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development
Uwe Marx,Akabane T,Tommy B. Andersson,Elizabeth Baker,Mario Beilmann,Beken S,Brendler-Schwaab S,Murat Cirit,Rhiannon David,Dehne Em,Isabell Durieux,Lorna Ewart,Suzanne Fitzpatrick,Olivier Frey,Florian Fuchs,Linda G. Griffith,Geraldine A. Hamilton,Thomas Hartung,Julia Hoeng,Helena T. Hogberg,David J. Hughes,Donald E. Ingber,Anita R. Iskandar,Toshiyuki Kanamori,Kojima H,Kuehnl J,Marcel Leist,Li B,Peter Loskill,Donna L. Mendrick,Neumann T,Giorgia Pallocca,Ivan Rusyn,Lena Smirnova,Thomas Steger-Hartmann,Danilo A. Tagle,Alexander G. Tonevitsky,Tsyb S,Trapecar M,van de Water B,Van den Eijnden-van Raaij J,Paul Vulto,Watanabe K,Wolf A,Zhou X,Adrian Roth +45 more
TL;DR: It is found that the level of qualification of MPS-based assays for a given context of use and communication gaps between stakeholders are the major challenges slowing industrial adoption by end users, which in turn is causing a regulatory acceptance dilemma.
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Multi-analyte biosensor interface for real-time monitoring of 3D microtissue spheroids in hanging-drop networks.
TL;DR: The proposed technology enabled tissue-size-dependent, real-time detection of lactate secretion from single human colon cancer microtissues cultured in the hanging drops, and the impact of different culture conditions on the metabolism of cancer microTissues was recorded in real- time.