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Paul G. Richardson

Researcher at Harvard University

Publications -  1631
Citations -  174221

Paul G. Richardson is an academic researcher from Harvard University. The author has contributed to research in topics: Multiple myeloma & Bortezomib. The author has an hindex of 183, co-authored 1533 publications receiving 155912 citations. Previous affiliations of Paul G. Richardson include Broomfield Hospital & Dartmouth College.

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An inhibitor of proteasome β2 sites sensitizes myeloma cells to immunoproteasome inhibitors.

TL;DR: It is reported here that pharmacologically relevant concentrations of β5i-specific inhibitor ONX-0914 show cytotoxicity in MM cell lines similar to that of carfilzomib and bortezomib, and synergizes with all FDA-approved proteasome inhibitors in MM in vitro and in vivo.
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Painful tongue ulcerations in patients with bisphosphonate-associated osteonecrosis of the jaws

TL;DR: Oral health care specialists and physicians must be alert to this potential complication of BONJ because it is easily managed with conservative measures and results in rapid and significant improvement in symptoms and overall quality of life.
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Performance of the International Myeloma Working Group myeloma frailty score among patients 75 and older.

TL;DR: The results suggest that using age as a criterion to identify frailty in older patients with multiple myeloma may limit treatment options for the functionally vigorous.