P
Paul G. Richardson
Researcher at Harvard University
Publications - 1631
Citations - 174221
Paul G. Richardson is an academic researcher from Harvard University. The author has contributed to research in topics: Multiple myeloma & Bortezomib. The author has an hindex of 183, co-authored 1533 publications receiving 155912 citations. Previous affiliations of Paul G. Richardson include Broomfield Hospital & Dartmouth College.
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Journal ArticleDOI
Resolving the daratumumab interference with blood compatibility testing.
Claudia I. Chapuy,Rachel T. Nicholson,Maria Aguad,Bjoern Chapuy,Jacob P. Laubach,Paul G. Richardson,Parul Doshi,Richard M. Kaufman +7 more
TL;DR: It is hypothesized that the observed panreactivity reflected DARA binding to CD38 on reagent RBCs, and methods to prevent this binding are investigated.
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Management of relapsed multiple myeloma: recommendations of the International Myeloma Working Group
Jacob P. Laubach,Laurent Garderet,Anuj Mahindra,Gösta Gahrton,Jo Caers,O. Sezer,Peter M. Voorhees,Xavier Leleu,Hans Erik Johnsen,Matthew Streetly,Artur Jurczyszyn,Heinz Ludwig,U. H. Mellqvist,W. J. Chng,Linda M. Pilarski,H. Einsele,J. Hou,Ingemar Turesson,Elena Zamagni,C. S. Chim,Amitabha Mazumder,Jan Westin,Jiachuan Lu,Tony Reiman,Sigurdur Y. Kristinsson,Douglas E. Joshua,Murielle Roussel,Peter O'Gorman,E. Terpos,P.L. McCarthy,M.A. Dimopoulos,Philippe Moreau,Robert Z. Orlowski,J. S. Miguel,KC Anderson,Antonio Palumbo,Shaji Kumar,Vincent Rajkumar,Brian G.M. Durie,Paul G. Richardson +39 more
TL;DR: This comprehensive manuscript from the International Myeloma Working Group provides detailed recommendations on management of relapsed disease, with sections dedicated to diagnostic evaluation, determinants of therapy, and general approach to patients with specific disease characteristics.
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Bortezomib in combination with dexamethasone for the treatment of patients with relapsed and/or refractory multiple myeloma with less than optimal response to bortezomib alone
Sundar Jagannath,Paul G. Richardson,Bart Barlogie,James R. Berenson,Seema Singhal,David Irwin,Gordan Srkalovic,David P. Schenkein,Dixie Lee Esseltine,Kenneth C. Anderson +9 more
TL;DR: Addition of dexamethasone to bortezomib in patients with relapsed and/or refractory multiple myeloma who had suboptimal responses to bortsomib alone was associated with improvement in responses without prohibitive toxicity.
Journal ArticleDOI
Assembly of viral metagenomes from yellowstone hot springs.
Thomas W. Schoenfeld,Melodee Patterson,Paul G. Richardson,K. Eric Wommack,Mark J. Young,David A. Mead +5 more
TL;DR: Analysis of coding sequences suggests lytic viruses are more common in geothermal environments than previously thought, and is the first application of metagenomics to viruses of geothermal origin.
Journal ArticleDOI
IMWG consensus on maintenance therapy in multiple myeloma
Heinz Ludwig,Brian G.M. Durie,Philip L. McCarthy,Antonio Palumbo,Jesús F. San Miguel,Bart Barlogie,Gareth J. Morgan,Pieter Sonneveld,Andrew Spencer,Kenneth C. Andersen,Thierry Facon,A. Keith Stewart,Hermann Einsele,Maria-Victoria Mateos,Pierre W. Wijermans,Anders Waage,Meral Beksac,Paul G. Richardson,Cyrille Hulin,Ruben Niesvizky,Henk M. Lokhorst,Ola Landgren,P. Leif Bergsagel,Robert Z. Orlowski,Axel Hinke,Michele Cavo,Michel Attal +26 more
TL;DR: Thalidomide maintenance therapy after autologous stem cell transplantation improved the quality of response and increased progression-free survival significantly in all 6 studies and overall survival in 3 of them and in elderly patients, 2 trials showed a significant prolongation of PFS, but no improvement in OS.