P
Paul J. van Diest
Researcher at Utrecht University
Publications - 514
Citations - 22750
Paul J. van Diest is an academic researcher from Utrecht University. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 70, co-authored 459 publications receiving 18892 citations. Previous affiliations of Paul J. van Diest include University Medical Center Utrecht & VU University Medical Center.
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Journal ArticleDOI
Prognostic value of mitotic index and Bcl2 expression in male breast cancer.
Miangela M. Lacle,Carmen C. van der Pol,Arjen J. Witkamp,Elsken van der Wall,Paul J. van Diest +4 more
TL;DR: Bcl2 expression is common in MBC, but is not associated with major clinicopathologic features and, in contrast to FBC, does not seem to have prognostic value, also when combined with mitotic index.
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Network Meta-analysis for the Diagnostic Approach to Pathologic Nipple Discharge.
Mando D. Filipe,Susanna I.S. Patuleia,Valentijn M.T. de Jong,M. R. Vriens,Paul J. van Diest,Arjen J. Witkamp +5 more
TL;DR: Results from this network meta-analysis indicate that although ultrasound and mammogram may remain low-cost useful first choices for the detection of malignancy in patients with PND, ductoscopy outperforms most imaging techniques (especially MRI) and cytology.
Journal Article
Value of histopathologic analysis of skin excisions by GPs.
TL;DR: All skin excisions by GPs must undergo routine histopathological investigation to ensure that serious malignancies are not missed, with a high percentage of unexpected pre-malignancies and malignant in patients below and above the age of 40 years.
Journal ArticleDOI
Do columnar cell lesions exist in the male breast
Anoek H J Verschuur-Maes,Robert Kornegoor,Peter C. de Bruin,Joost J. Oudejans,Paul J. van Diest +4 more
TL;DR: In females, columnar cell lesions (CCLs) have been recognized as putative precursor lesions of low‐grade breast cancer, but their role in male breast carcinogenesis is as yet unclear.
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Tumor-Infiltrating Lymphocytes in Low-Risk Patients With Breast Cancer Treated With Single-Dose Preoperative Partial Breast Irradiation.
Jeanine E. Vasmel,Celien P.H. Vreuls,Quirine F. Manson,Ramona K. Charaghvandi,Joost van Gorp,A.M. Gijs van Leeuwen,Paul J. van Diest,Helena M. Verkooijen,H.J.G. Desiree van den Bongard +8 more
TL;DR: After pre-operative PBI in this limited cohort of low-risk breast cancer patients, the number of TILs in tumor tissue decreased, and no differences in numbers of pre-irradiation Tils between responders and non-responders were observed.