P
Paul J. van Diest
Researcher at Utrecht University
Publications - 514
Citations - 22750
Paul J. van Diest is an academic researcher from Utrecht University. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 70, co-authored 459 publications receiving 18892 citations. Previous affiliations of Paul J. van Diest include University Medical Center Utrecht & VU University Medical Center.
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Journal ArticleDOI
Isolated tumor cells in breast cancer sentinel lymph nodes: displacement or metastases? An immunohistochemical study.
Carolien H.M. van Deurzen,Peter C. de Bruin,R. Koelemij,Richard van Hillegersberg,Paul J. van Diest +4 more
TL;DR: Evaluation of isolated tumor cells by immunohistochemistry for proteins often overexpressed in breast cancer such as cyclin D1 and p53 supports the hypothesis that some of these cells may be displaced benign cells or concern tumor cells with limited malignant potential compared with micro- and macrometastases.
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Quantifying the Mitigating Effects of Whole-Breast Radiotherapy and Systemic Treatments on Regional Recurrence Incidence Among Breast Cancer Patients
Julia E.C. van Steenhoven,Anne Kuijer,Marissa C. van Maaren,Marleen M. Roos,Sjoerd G. Elias,Paul J. van Diest,Sabine Siesling,Marjolein L. Smidt,Liesbeth J. Boersma,Thijs van Dalen +9 more
TL;DR: RT as routine part of BCT, chemotherapy, and hormonal therapy independently exerted a mitigating effect on the risk for the development of RR, which at least halved the risk of RR among SLNB-negative breast cancer patients.
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Histopathology of breast cancer after magnetic resonance-guided high-intensity focused ultrasound and radiofrequency ablation
Floortje M. Knuttel,Laurien Waaijer,Laura G. Merckel,Maurice A.A.J. van den Bosch,Arjen J. Witkamp,Roel Deckers,Paul J. van Diest +6 more
TL;DR: This study aimed to compare histopathological features of breast cancer after MR‐HIFU ablation and RFA.
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Imaging to predict checkpoint inhibitor outcomes in cancer. A systematic review.
L. S. Ter Maat,I. V. van Duin,Sjoerd G. Elias,Paul J. van Diest,Josien P. W. Pluim,Joost J.C. Verhoeff,Pim A. de Jong,Tim Leiner,Mitko Veta,Karijn P M Suijkerbuijk +9 more
TL;DR: In this paper , the authors present a systematic review of the current evidence on imaging biomarkers that predict response and survival in patients treated with checkpoint inhibitors in all cancer types, including melanoma and lung cancer.
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Detecting breast microcalcifications with high-field MRI
Hendrik de Leeuw,Hendrik de Leeuw,Bertine L. Stehouwer,Chris J.G. Bakker,Dennis W. J. Klomp,Paul J. van Diest,Peter R. Luijten,Peter R. Seevinck,Maurice A.A.J. van den Bosch,Max A. Viergever,Wouter B. Veldhuis +10 more
TL;DR: Microcalcifications can be detected by MRI in human whole breast specimens by the application of phase derivative imaging through gradient‐echo MRI acquisitions on a high‐field MR scanner.