Paul J. van Diest

TL;DR: HIF-1α overexpression is an indicator of favourable prognosis in T1 and T2 SCC of the oral floor and node negative patients lacking HIF- 1α expression may therefore be considered for adjuvant radiotherapy.

TL;DR: In this article, the effect of intrahepatic I/R on the outgrowth of pre-established colorectal micrometastases in a highly standardized murine model and the putative protective effect of alternative clamping methods were evaluated.

TL;DR: It is shown here that cytosolic p120-catenin (p120) regulates tumor growth upon loss of E-cadherin through the induction of anoikis resistance, and this insight may have clinical implications for the development of tailor-made intervention strategies to better treat invasive and metastatic lobular breast cancer.

TL;DR: Comparative genomic hybridization was used to screen ductal hyperplasia and other BPBD lesions and ductal carcinoma in situ (DCIS) for common genomic abnormalities, to test the relationship between these hyperplastic and neoplastic lesions and support the view thatBPBD and DCIS are not closely related entities and that BPBD is not an obligate direct precursor of DCIS.

TL;DR: Most male breast cancers are luminal A and luminal B types, whereas basal-like, unclassifiable triple-negative, and HER2 driven male breast cancer are rare.