P
Paul J. van Diest
Researcher at Utrecht University
Publications - 514
Citations - 22750
Paul J. van Diest is an academic researcher from Utrecht University. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 70, co-authored 459 publications receiving 18892 citations. Previous affiliations of Paul J. van Diest include University Medical Center Utrecht & VU University Medical Center.
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Journal ArticleDOI
Expression and localization of hypoxia proteins in prostate cancer: prognostic implications after radical prostatectomy.
Judith J.M. Jans,Jessica H. van Dijk,Susanne J. van Schelven,Petra van der Groep,Sofie H. Willems,Trudy N. Jonges,Paul J. van Diest,J.L.H. Ruud Bosch +7 more
TL;DR: This study confirms the upregulation of proteins involved in the HIF-1α hypoxia pathway in prostate cancer cells, indicative of a hypoxic tumor state, and identifies 2 novel markers, GLUT1 and prolyl-4-hydroxylases 1, with prognostic significance for patients undergoing radical prostatectomy.
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Immunophenotyping of male breast cancer.
Robert Kornegoor,Anoek H J Verschuur-Maes,Horst Buerger,Marieke C H Hogenes,Peter C. de Bruin,Joost J. Oudejans,Bernd Hinrichs,Paul J. van Diest +7 more
TL;DR: Histopathology’sImmunophenotyping of male breast cancer and the role of EMT and ‘cell reprograming’ in the development of breast cancer is described.
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Desmoid-type fibromatosis of the head and neck region in the paediatric population: a clinicopathological and genetic study of seven cases.
TL;DR: Desmoid‐type fibromatosis (desmoid) is a locally aggressive (myo)fibroblastic lesion that represents one of the more common fibrous tumours in children and adolescents.
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Expression of nuclear FIH independently predicts overall survival of clear cell renal cell carcinoma patients.
Stephanie G.C. Kroeze,Joost S.P. Vermaat,Aram S. A. van Brussel,Harm H.E. van Melick,Emile E. Voest,Trudy N. Jonges,Paul J. van Diest,John W. J. Hinrichs,J.L.H. Ruud Bosch,Judith J.M. Jans +9 more
TL;DR: It is shown that low nuclear expression of FIH is a strong independent prognostic factor for a poor overall survival in ccRCC.
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Whole slide images for primary diagnostics of paediatric pathology specimens: A feasibility study
TL;DR: Primary diagnostics of paediatric tissue biopsies and resections can generally well be done on WSI, however, some difficulties were encountered in examining placenta tissue where the identification of nucleated red blood cells may need higher resolution or even scanning at multiple focus depths, which is well possible on most current slide scanners.