P
Paul J. van Diest
Researcher at Utrecht University
Publications - 514
Citations - 22750
Paul J. van Diest is an academic researcher from Utrecht University. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 70, co-authored 459 publications receiving 18892 citations. Previous affiliations of Paul J. van Diest include University Medical Center Utrecht & VU University Medical Center.
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Journal ArticleDOI
Assessment of algorithms for mitosis detection in breast cancer histopathology images
Mitko Veta,Paul J. van Diest,Stefan M. Willems,Haibo Wang,Anant Madabhushi,Angel Cruz-Roa,Fabio A. González,Anders Boesen Lindbo Larsen,Jacob S. Vestergaard,Anders Bjorholm Dahl,Dan Ciresan,Jürgen Schmidhuber,Alessandro Giusti,Luca Maria Gambardella,F. Boray Tek,Thomas Walter,Thomas Walter,Thomas Walter,Ching-Wei Wang,Satoshi Kondo,Satoshi Kondo,Bogdan J. Matuszewski,Frédéric Precioso,Violet Snell,Josef Kittler,Teofilo de Campos,Teofilo de Campos,Adnan Mujahid Khan,Nasir M. Rajpoot,Nasir M. Rajpoot,Evdokia Arkoumani,Miangela M. Lacle,Max A. Viergever,Josien P. W. Pluim +33 more
TL;DR: The results from the Assessment of Mitosis Detection Algorithms 2013 (AMIDA13) challenge are described and the top performing method has an error rate that is comparable to the inter-observer agreement among pathologists.
Journal ArticleDOI
The 2019 World Health Organization classification of tumours of the breast.
Puay Hoon Tan,Ian O. Ellis,Kimberly H. Allison,Edi Brogi,Stephen B. Fox,Sunil R. Lakhani,Alexander J. Lazar,Elizabeth A. Morris,Aysegul Sahin,Roberto Salgado,Anna Sapino,Hironobu Sasano,Stuart J. Schnitt,Christos Sotiriou,Paul J. van Diest,Valerie A. White,Dilani Lokuhetty,Ian A. Cree +17 more
TL;DR: The newly published World Health Organization (WHO) Classification of Tumours of the breast features significant changes compared to earlier editions, and this review outlines the major changes.
Journal ArticleDOI
Automatic Nuclei Segmentation in H&E Stained Breast Cancer Histopathology Images
Mitko Veta,Paul J. van Diest,Robert Kornegoor,André Huisman,Max A. Viergever,Josien P. W. Pluim +5 more
TL;DR: An automated nuclei segmentation method that works with hematoxylin and eosin stained breast cancer histopathology images, which represent regions of whole digital slides, is developed.
Journal ArticleDOI
Twist is a transcriptional repressor of E-cadherin gene expression in breast cancer
TL;DR: It is demonstrated that Twist can transcriptionally repress E-cadherin in breast cancer cells using transient promoter assays and that this regulation was verified by quantitative real-time PCR and immunohistochemistry on a cohort of cancer samples.
Journal ArticleDOI
Supplemental MRI Screening for Women with Extremely Dense Breast Tissue
Marije F. Bakker,Stéphanie V de Lange,Ruud M. Pijnappel,Ritse M. Mann,Petra H.M. Peeters,Evelyn M. Monninkhof,Marleen J. Emaus,Claudette E. Loo,Robertus H.C. Bisschops,Marc B. I. Lobbes,Matthijn D.F. de Jong,Katya M. Duvivier,Jeroen Veltman,Nico Karssemeijer,Harry J. de Koning,Paul J. van Diest,Willem P.Th.M. Mali,Maurice A.A.J. van den Bosch,Wouter B. Veldhuis,Carla H. van Gils +19 more
TL;DR: The use of supplemental MRI screening in women with extremely dense breast tissue and normal results on mammography resulted in the diagnosis of significantly fewer interval cancers than mammography alone during a 2-year screening period.