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Paul Wilmes
Researcher at University of Luxembourg
Publications - 172
Citations - 13624
Paul Wilmes is an academic researcher from University of Luxembourg. The author has contributed to research in topics: Microbiome & Metagenomics. The author has an hindex of 44, co-authored 140 publications receiving 10102 citations. Previous affiliations of Paul Wilmes include Arizona's Public Universities & Institute for Systems Biology.
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Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota
Koji Atarashi,Takeshi Tanoue,Kenshiro Oshima,Wataru Suda,Yuji Nagano,Hiroyoshi Nishikawa,Shinji Fukuda,Takuro Saito,Seiko Narushima,Koji Hase,Sangwan Kim,Joëlle V. Fritz,Paul Wilmes,Satoshi Ueha,Kouji Matsushima,Hiroshi Ohno,Bernat Olle,Shimon Sakaguchi,Tadatsugu Taniguchi,Hidetoshi Morita,Masahira Hattori,Kenya Honda +21 more
TL;DR: Using a rational approach to isolate CD4+FOXP3+ regulatory T (Treg)-cell-inducing bacterial strains from the human indigenous microbiota may allow for tailored therapeutic manipulation of human immune disorders.
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A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility
Mahesh Desai,Mahesh Desai,Anna M. Seekatz,Nicole M. Koropatkin,Nobuhiko Kamada,Christina A. Hickey,Mathis Wolter,Nicholas A. Pudlo,Sho Kitamoto,Nicolas Terrapon,Arnaud Muller,Vincent B. Young,Bernard Henrissat,Paul Wilmes,Thaddeus S. Stappenbeck,Gabriel Núñez,Eric C. Martens +16 more
TL;DR: Dietary fiber deprivation, together with a fiber-deprived, mucus-eroding microbiota, promotes greater epithelial access and lethal colitis by the mucosal pathogen, Citrobacter rodentium.
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Generation of genome-scale metabolic reconstructions for 773 members of the human gut microbiota
Stefania Magnusdottir,Almut Heinken,Laura Kutt,Dmitry A. Ravcheev,Eugen Bauer,Alberto Noronha,Kacy Greenhalgh,Christian Jäger,Joanna Baginska,Paul Wilmes,Ronan M. T. Fleming,Ines Thiele +11 more
TL;DR: This work presents AGORA (assembly of gut organisms through reconstruction and analysis), a resource of genome-scale metabolic reconstructions semi-automatically generated for 773 human gut bacteria, and identified a defined growth medium for Bacteroides caccae ATCC 34185.
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A microfluidics-based in vitro model of the gastrointestinal human-microbe interface.
Pranjul Shah,Joëlle V. Fritz,Enrico Glaab,Mahesh Desai,Kacy Greenhalgh,Audrey Frachet,Magdalena Niegowska,Matthew Estes,Christian Jäger,Carole Seguin-Devaux,Frederic Zenhausern,Paul Wilmes +11 more
TL;DR: The ability of HuMiX to recapitulate in vivo transcriptional, metabolic and immunological responses in human intestinal epithelial cells following their co-culture with the commensal Lactobacillus rhamnosus GG (LGG) grown under anaerobic conditions is demonstrated.
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VizBin - an application for reference-independent visualization and human-augmented binning of metagenomic data.
Cedric Christian Laczny,Tomasz Sternal,Valentin Plugaru,Piotr Gawron,Arash Atashpendar,Houry Hera Margossian,Sergio Coronado,Laurens van der Maaten,Nikos Vlassis,Paul Wilmes +9 more
TL;DR: VizBin can be applied de novo for the visualization and subsequent binning of metagenomic datasets from single samples, and it can be used for the post hoc inspection and refinement of automatically generated bins.