P
Peiwen Cai
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 4
Citations - 460
Peiwen Cai is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Gene & Viral entry. The author has an hindex of 2, co-authored 2 publications receiving 272 citations. Previous affiliations of Peiwen Cai include Mount Sinai Hospital.
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Integrated analyses of single-cell atlases reveal age, gender, and smoking status associations with cell type-specific expression of mediators of SARS-CoV-2 viral entry and highlights inflammatory programs in putative target cells
Pascal Barbry,Christoph Muus,Christoph Muus,Malte D Luecken,Gökcen Eraslan,Avinash Waghray,Graham Heimberg,Lisa Sikkema,Yoshihiko Kobayashi,Eeshit Dhaval Vaishnav,Ayshwarya Subramanian,Christopher Smilie,Karthik A. Jagadeesh,Elizabeth Thu Duong,Evgenij Fiskin,Elena Torlai Triglia,Meshal Ansari,Peiwen Cai,Brian M. Lin,Justin Buchanan,Sijia Chen,Jian Shu,Jian Shu,Adam L. Haber,Adam L. Haber,Hattie Chung,Daniel T. Montoro,Taylor Adams,Hananeh Aliee,J. Samuel,Allon Zaneta Andrusivova,Ilias Angelidis,Orr Ashenberg,Kevin Bassler,Christophe Bécavin,Inbal Benhar,Joseph Bergenstråhle,Ludvig Bergenstråhle,Liam Bolt,Emelie Braun,Linh T. Bui,Mark Chaffin,Evgeny Chichelnitskiy,Joshua Chiou,Thomas M. Conlon,Michael S. Cuoco,Marie Deprez,David Fischer,Astrid Gillich,Joshua Gould,Minzhe Guo,Austin J. Gutierrez,Arun C. Habermann,Tyler Harvey,Peng He,Xiaomeng Hou,Xiaomeng Hou,Lijuan Hu,Alok Jaiswal,Peiyong Jiang,Theodoros Kapellos,Christin S. Kuo,Ludvig Larsson,Michael Leney-Greene,Kyungtae Lim,Monika Litviňuková,Monika Litviňuková,Ji Lu,Leif S. Ludwig,Wendy Luo,Henrike Maatz,Elo Madissoon,Lira Mamanova,Kasidet Manakongtreecheep,Kasidet Manakongtreecheep,Charles-Hugo Marquette,Ian Mbano,Alexi McAdams,Ross J. Metzger,Ahmad N. Nabhan,Sarah K. Nyquist,Lolita Penland,Olivier Poirion,Sergio Poli,Cancan Qi,Rachel Queen,Daniel Reichart,Daniel Reichart,Ivan O. Rosas,Jonas C. Schupp,Rahul Sinha,Rene Sit,Kamil Slowikowski,Kamil Slowikowski,Michal Slyper,Neal Smith,Neal Smith,Alex Sountoulidis,Maximilian Strunz,Dawei Sun,Carlos Talavera-López,Peng Tan,Jessica Tantivit,Jessica Tantivit,Kyle J. Travaglini,Nathan R. Tucker,Katherine A. Vernon,Katherine A. Vernon,Marc Wadsworth,Julia Waldman,Xiuting Wang,Wenjun Yan,William Zhao,Carly Ziegler +113 more
TL;DR: Differences in the cell type-specific expression of mediators of SARS-CoV-2 viral entry may be responsible for aspects of COVID-19 epidemiology and clinical course, and point to putative molecular pathways involved in disease susceptibility and pathogenesis.
Journal ArticleDOI
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics.
Christoph Muus,Malte D Luecken,Gökcen Eraslan,Lisa Sikkema,Avinash Waghray,Graham Heimberg,Yoshihiko Kobayashi,Eeshit Dhaval Vaishnav,Eeshit Dhaval Vaishnav,Ayshwarya Subramanian,Christopher Smillie,Karthik A. Jagadeesh,Elizabeth Thu Duong,Evgenij Fiskin,Elena Torlai Triglia,Meshal Ansari,Peiwen Cai,Brian M. Lin,Justin Buchanan,Sijia Chen,Jian Shu,Adam L. Haber,Adam L. Haber,Hattie Chung,Daniel T. Montoro,Taylor Adams,Hananeh Aliee,Samuel J. Allon,Samuel J. Allon,Samuel J. Allon,Zaneta Andrusivova,Ilias Angelidis,Orr Ashenberg,Kevin Bassler,Christophe Bécavin,Inbal Benhar,Joseph Bergenstråhle,Ludvig Bergenstråhle,Liam Bolt,Emelie Braun,Linh T. Bui,Steven Callori,Mark Chaffin,Evgeny Chichelnitskiy,Joshua Chiou,Thomas M. Conlon,Michael S. Cuoco,Anna S E Cuomo,Marie Deprez,Grant Duclos,Denise Fine,David S. Fischer,Shila Ghazanfar,Astrid Gillich +53 more
TL;DR: In this paper, cell-type-specific expression of ACE2, TMPRSS2 and CTSL across 107 single-cell RNA-sequencing studies from different tissues was assessed.
Journal ArticleDOI
An atlas of late prenatal human neurodevelopment resolved by single-nucleus transcriptomics
Susana Ramos,Zarmeen Mussa,Elisa N. Falk,Balagopal Pai,Bruno Giotti,Kimaada Allette,Peiwen Cai,Fumiko Dekio,Robert Sebra,Kristin G. Beaumont,Alexander M. Tsankov,Nadejda M. Tsankova +11 more
TL;DR: In this paper , a single-nucleus RNA sequencing atlas of over 200,000 nuclei derived from the proliferative germinal matrix and laminating cortical plate of 15 prenatal, non-pathological postmortem samples from 17 to 41 gestational weeks, and 3 adult controls is presented.
Journal ArticleDOI
Peripheral NOD-like receptor deficient inflammatory macrophages trigger neutrophil infiltration into the brain disrupting daytime locomotion
Victoria Kwon,Peiwen Cai,Cameron T. Dixon,Victoria Hamlin,Caroline G. Spencer,Alison M. Rojas,Matthew Hamilton,Celia E. Shiau +7 more
TL;DR: This article investigated whether inappropriate macrophage-evoked inflammation alters CNS control of daily-life animal locomotion using a set of zebrafish mutants selected for specific macrophages dysfunction and microglia deficiency.