Q
Que Lan
Researcher at University of Wisconsin-Madison
Publications - 31
Citations - 914
Que Lan is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Sterol carrier protein & Aedes aegypti. The author has an hindex of 16, co-authored 31 publications receiving 795 citations.
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Journal ArticleDOI
Multifaceted biological insights from a draft genome sequence of the tobacco hornworm moth, Manduca sexta
Michael R. Kanost,Estela L. Arrese,Xiaolong Cao,Yun-Ru Chen,Sanjay Chellapilla,Marian R. Goldsmith,Ewald Grosse-Wilde,David G. Heckel,Nicolae Herndon,Haobo Jiang,Alexie Papanicolaou,Jiaxin Qu,Jose L. Soulages,Heiko Vogel,James R. Walters,Robert M. Waterhouse,Seung-Joon Ahn,Francisca C. Almeida,Chunju An,Peshtewani K. Aqrawi,Anne Bretschneider,William B. Bryant,Sascha Bucks,Hsu Chao,Germain Chevignon,Jayne M. Christen,David F. Clarke,Neal T. Dittmer,Laura Ferguson,Spyridoula Garavelou,Karl H.J. Gordon,Ramesh T. Gunaratna,Yi Han,Frank Hauser,Yan He,Hanna M. Heidel-Fischer,Ariana Hirsh,Yingxia Hu,Hongbo Jiang,Divya Kalra,Christian Klinner,Christopher König,Christie Kovar,Ashley R. Kroll,Suyog S. Kuwar,Sandy Lee,Rüdiger Lehman,Kai Li,Zhaofei Li,Hanquan Liang,Shanna Lovelace,Zhiqiang Lu,Jennifer H. Mansfield,Kyle J. McCulloch,Tittu Mathew,Brian R. Morton,Donna M. Muzny,David Neunemann,Fiona Ongeri,Yannick Pauchet,Ling Ling Pu,Ioannis Pyrousis,Xiang Jun Rao,Amanda J. Redding,Charles Roesel,Alejandro Sánchez-Gracia,Sarah Schaack,Aditi Shukla,Guillaume Tetreau,Yang Wang,Guang Hua Xiong,Walther Traut,Tom Walsh,Kim C. Worley,Di Wu,Wenbi Wu,Yuan Qing Wu,Xiufeng Zhang,Zhen Zou,Hannah Zucker,Adriana D. Briscoe,Thorsten Burmester,Rollie J. Clem,René Feyereisen,Cornelis J. P. Grimmelikhuijzen,Stavros J. Hamodrakas,Bill S. Hansson,Elisabeth Huguet,Lars S. Jermiin,Que Lan,Herman K. Lehman,Marcé D. Lorenzen,Hans Merzendorfer,Ioannis Michalopoulos,David B. Morton,Subbaratnam Muthukrishnan,John G. Oakeshott,William J. Palmer,Yoonseong Park,A. Lorena Passarelli,Julio Rozas,Lawrence M. Schwartz,Wendy A. Smith,Agnes Ayme Southgate,Andreas Vilcinskas,Richard G. Vogt,Ping Wang,John H. Werren,Xiao-Qiang Yu,Jing-Jiang Zhou,Susan J. Brown,Steven E. Scherer,Stephen Richards,Gary W. Blissard +113 more
TL;DR: The sequence and annotation of the M. sexta genome, and a survey of gene expression in various tissues and developmental stages, provide an important new resource from a well-studied model insect species and will facilitate further biochemical and mechanistic experimental studies of many biological systems in insects.
Journal ArticleDOI
The Structural Determination of an Insect Sterol Carrier Protein-2 with a Ligand-bound C16 Fatty Acid at 1.35-Å Resolution
TL;DR: The present study suggests that the binding pocket in the SCP-2 family of proteins may exhibit conformational flexibility to allow coordination of a variety of lipids.
Journal ArticleDOI
Regulatory mechanisms of chitin biosynthesis and roles of chitin in peritrophic matrix formation in the midgut of adult Aedes aegypti.
Nobutaka Kato,Christopher R. Mueller,Jeremy F. Fuchs,Vilena Wessely,Que Lan,Bruce M. Christensen +5 more
TL;DR: It is demonstrated that formation of the peritrophic matrix is disrupted when the transcript abundance of either gene is knocked-down using RNAi methodologies, and chitin biosynthesis is negatively regulated, in part, by inhibitory sensitivity of AeGFAT-1 to UDP-N-acetylglucosamine.
Journal ArticleDOI
Isolation and expression of a sterol carrier protein-2 gene from the yellow fever mosquito, Aedes aegypti.
Kendall Krebs,Que Lan +1 more
TL;DR: A putative mosquito sterol carrier protein‐2 (SCP‐2) cDNA from fourth instar subtracted cDNA library is identified, which has high degree homology in the sterol transfer domain to both rat and human SCP‐2.
Journal ArticleDOI
Functional analysis of AeSCP-2 using gene expression knockdown in the yellow fever mosquito, Aedes aegypti.
TL;DR: Results from this study indicate that AeSCP‐2 is important for adult development and for the viability of the eggs.