R
Rajkumar Verma
Researcher at University of Connecticut Health Center
Publications - 42
Citations - 1582
Rajkumar Verma is an academic researcher from University of Connecticut Health Center. The author has contributed to research in topics: Stroke & Neuroprotection. The author has an hindex of 16, co-authored 35 publications receiving 1105 citations. Previous affiliations of Rajkumar Verma include University of Connecticut & Hartford Hospital.
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Journal ArticleDOI
Synaptopathies: synaptic dysfunction in neurological disorders - A review from students to students
Katarzyna Lepeta,Mychael V. Lourenco,Barbara Schweitzer,Pamela V. Martino Adami,Priyanjalee Banerjee,Silvina Catuara-Solarz,Mario de la Fuente Revenga,Alain M. Guillem,Mouna Haidar,Omamuyovwi M. Ijomone,Bettina Nadorp,Lin Qi,Nirma D Perera,Louise K. Refsgaard,Kimberley M. Reid,Mariam Sabbar,Arghyadip Sahoo,Natascha Schaefer,Rebecca K. Sheean,Anna Suska,Rajkumar Verma,Cinzia Vicidomini,Dean J. Wright,Xingding Zhang,Constanze I. Seidenbecher +24 more
TL;DR: Basic concepts of synapse structure and function are discussed, and a critical view of how aberrant synapse physiology may contribute to neurodevelopmental disorders as well as neurodegenerative disorders are provided.
Journal ArticleDOI
Functional differences between microglia and monocytes after ischemic stroke
Rodney M. Ritzel,Anita Patel,Jeremy M. Grenier,Joshua Crapser,Rajkumar Verma,Evan R. Jellison,Louise D. McCullough +6 more
TL;DR: The resident microglia population is vulnerable to the effects of severe ischemia, show compromised cell cycle progression, and adopt a largely pro-inflammatory phenotype after stroke, suggesting that the early wave of infiltrating monocytes may be beneficial to stroke repair.
Journal ArticleDOI
Aging alters the immunological response to ischemic stroke
Rodney M. Ritzel,Yun-Ju Lai,Joshua Crapser,Anita Patel,Anna Schrecengost,Jeremy M. Grenier,Nickolas S. Mancini,Anthony Patrizz,Evan R. Jellison,Diego Morales-Scheihing,Venugopal Reddy Venna,Julia Kofler,Fudong Liu,Rajkumar Verma,Louise D. McCullough +14 more
TL;DR: It is suggested that age alters the immunological response to stroke, and that this can be reversed by manipulation of the peripheral immune cells in the bone marrow.
Journal ArticleDOI
Ischemic stroke induces gut permeability and enhances bacterial translocation leading to sepsis in aged mice.
Joshua Crapser,Rodney M. Ritzel,Rajkumar Verma,Venugopal Reddy Venna,Fudong Liu,Anjali Chauhan,Edward C. Koellhoffer,Anita Patel,Austin Ricker,Kendra Maas,Joerg Graf,Louise D. McCullough,Louise D. McCullough +12 more
TL;DR: While stroke induced gut permeability and bacterial translocation in both young and aged mice, only young mice were able to resolve infection and developed a septic response marked by persistent and exacerbated hypothermia, weight loss, and immune dysfunction compared to young mice following stroke.
Journal ArticleDOI
Neurochemical and molecular characterization of ketamine-induced experimental psychosis model in mice.
TL;DR: These analyses tend to support the "chronic ketamine" mice model for experimental psychosis as a tool for deeper investigation of the mechanistic paradigm associated with the schizophrenia spectrum disorder and for screening next-generation antipsychotic drugs.