R
Renee Escalona
Researcher at Texas Biomedical Research Institute
Publications - 6
Citations - 437
Renee Escalona is an academic researcher from Texas Biomedical Research Institute. The author has contributed to research in topics: Chemokine & Viral pathogenesis. The author has an hindex of 4, co-authored 6 publications receiving 130 citations.
Papers
More filters
Journal ArticleDOI
Lethality of SARS-CoV-2 infection in K18 human angiotensin-converting enzyme 2 transgenic mice.
Fatai S. Oladunni,Jun-Gyu Park,Paula A. Pino,Olga Gonzalez,Anwari Akhter,Anna Allué-Guardia,Angélica Olmo-Fontánez,Angélica Olmo-Fontánez,Shalini Gautam,Andreu Garcia-Vilanova,Chengjin Ye,Kevin Chiem,Kevin Chiem,Colwyn A. Headley,Varun Dwivedi,Laura M. Parodi,Kendra J. Alfson,Hilary M. Staples,Alyssa Schami,Alyssa Schami,Juan Ignacio García,Alison Whigham,Roy N. Platt,Michal Gazi,Jesse Martinez,Colin Chuba,Stephanie Earley,Oscar H. Rodriguez,Stephanie Davis Mdaki,Katrina N. Kavelish,Renee Escalona,Cory R. A. Hallam,Corbett Christie,Jean L. Patterson,Tim J. Anderson,Ricardo Carrion,Edward J. Dick,Shannan Hall-Ursone,Larry S. Schlesinger,Xavier Alvarez,Deepak Kaushal,Luis D. Giavedoni,Joanne Turner,Luis Martinez-Sobrido,Jordi B. Torrelles +44 more
TL;DR: Transgenic mice expressing human angiotensin-converting enzyme 2 by the human cytokeratin 18 promoter represent a susceptible rodent model and represent a suitable animal model for the study of viral pathogenesis and for identification and characterization of vaccines and antivirals for SARS-CoV-2 infection and associated severe COVID-19 disease.
Posted ContentDOI
Lethality of SARS-CoV-2 infection in K18 human angiotensin converting enzyme 2 transgenic mice
Fatai S. Oladunni,Jun-Gyu Park,Paula Pino Tamayo,Olga Gonzalez,Anwari Akhter,Anna Allué-Guardia,Angélica Olmo-Fontánez,Angélica Olmo-Fontánez,Shalini Gautam,Andreu Garcia-Vilanova,Chengjin Ye,Kevin Chiem,Kevin Chiem,Colwyn A. Headley,Varun Dwivedi,Laura M. Parodi,Kendra J. Alfson,Hilary M. Staples,Alyssa Schami,Alyssa Schami,Juan Ignacio García,Alison Whigham,Roy N. Platt,Michal Gazi,Jesse Martinez,Colin Chuba,Stephanie Earley,Oscar H. Rodriguez,Stephanie Davis Mdaki,Katrina N. Kavelish,Renee Escalona,Cory R. A. Hallam,Corbett Christie,Jean L. Patterson,Tim J. Anderson,Ricardo Carrion,Edward J. Dick,Shannan Hall-Ursone,Larry S. Schlesinger,Deepak Kaushal,Luis D. Giavedoni,Xavier Alvarez,Joanne Turner,Luis Martinez-Sobrido,Jordi B. Torrelles +44 more
TL;DR: K18 hACE2-transgenic mice are, therefore, highly susceptible to SARS-CoV-2 infection and represent a suitable animal model for the study of viral pathogenesis, and for identification and characterization of vaccines (prophylactic) and antivirals (therapeutics) for SARS/COVID-19 disease.
Journal ArticleDOI
Immunogenicity and Protective Efficacy of an Intranasal Live-attenuated Vaccine Against SARS-CoV-2.
Jun Gyu Park,Fatai S. Oladunni,Mohammed A. Rohaim,Mohammed A. Rohaim,Jayde Whittingham-Dowd,James Tollitt,Matthew D. Hodges,Nadin Fathallah,Muhsref Bakri Assas,Wafaa A. Alhazmi,Abdullah Almilaibary,Munir Iqbal,Pengxiang Chang,Renee Escalona,Vinay Shivanna,Jordi B. Torrelles,John J. Worthington,Lucy H. Jackson-Jones,Luis Martinez-Sobrido,Muhammad Munir +19 more
TL;DR: In this article, the authors evaluated a Newcastle disease virus (NDV)-based vectored-vaccine in mice and hamsters for its immunogenicity, safety, and protective efficacy against SARS-CoV-2.
Posted ContentDOI
Immunogenicity and Protective Efficacy of an Intranasal Live-attenuated Vaccine Against SARS-CoV-2 in Preclinical Animal Models
Jun-Guy Park,Fatai S. Oladunni,Mohammed A. Rohaim,Mohammed A. Rohaim,Jayde Whittingham-Dowd,James Tollitt,Bakri M. Assas,Wafaa A. Alhazmi,Abdullah Almilaibary,Munir Iqbal,Pengxiang Chang,Renee Escalona,Vinay Shivanna,Jordi B. Torrelles,John J. Worthington,Lucy H. Jackson-Jones,Luis Martinez-Sobrido,Muhammad Munir +17 more
TL;DR: In this article, the authors evaluated a Newcastle disease virus (NDV)-based intranasal vectored-vaccine in mice and hamsters for its immunogenicity, safety and protective efficacy in challenge studies with SARS-CoV-2.
Journal ArticleDOI
An efficient model of human endometriosis by induced unopposed estrogenicity in baboons
Hareesh B. Nair,Robert Baker,Michael A. Owston,Renee Escalona,Edward J. Dick,John L. VandeBerg,Klaus J. Nickisch +6 more
TL;DR: The data suggest that depleting progesterone levels in the endometrium will increase estrogen hyper-responsiveness that leads to increased endometriotic lesion progression in the baboon (Papio anubis) model.