R
Richard Moxon
Researcher at University of Oxford
Publications - 45
Citations - 3150
Richard Moxon is an academic researcher from University of Oxford. The author has contributed to research in topics: Haemophilus influenzae & Nucleic acid. The author has an hindex of 20, co-authored 44 publications receiving 2947 citations. Previous affiliations of Richard Moxon include John Radcliffe Hospital & University of Queensland.
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Journal ArticleDOI
The minimum information about a genome sequence (MIGS) specification.
Dawn Field,George M. Garrity,Tanya Gray,Norman Morrison,Jeremy D. Selengut,Peter Sterk,Tatiana Tatusova,Nicholas R. Thomson,Michael J. Allen,Samuel V. Angiuoli,Michael Ashburner,Nelson Axelrod,Sandra L. Baldauf,S. Ballard,Jeffrey L. Boore,Guy Cochrane,James R. Cole,Peter Dawyndt,Paul De Vos,Claude W. dePamphilis,Robert Edwards,Nadeem Faruque,Robert G. Feldman,Jack A. Gilbert,Paul Gilna,Frank Oliver Glöckner,Philip Goldstein,Robert P. Guralnick,Daniel H. Haft,David Hancock,Henning Hermjakob,Christiane Hertz-Fowler,Phil Hugenholtz,Ian Joint,Leonid Kagan,Matthew D. Kane,Jessie Kennedy,George A. Kowalchuk,Renzo Kottmann,Eugene Kolker,Saul A. Kravitz,Nikos C. Kyrpides,Jim Leebens-Mack,Suzanna E. Lewis,Kelvin Li,Allyson L. Lister,Phillip Lord,Natalia Maltsev,Victor Markowitz,Jennifer B. H. Martiny,Barbara A. Methé,Ilene Mizrachi,Richard Moxon,Karen E. Nelson,Julian Parkhill,Lita M. Proctor,Owen White,Susanna-Assunta Sansone,Andrew J. Spiers,Robert Stevens,Paul Swift,Chris F. Taylor,Yoshio Tateno,Adrian Tett,Sarah L. Turner,David W. Ussery,Bob Vaughan,Naomi L. Ward,Trish Whetzel,Ingio San Gil,Gareth A. Wilson,Anil Wipat +71 more
TL;DR: Here, the minimum information about a genome sequence (MIGS) specification is introduced with the intent of promoting participation in its development and discussing the resources that will be required to develop improved mechanisms of metadata capture and exchange.
Journal ArticleDOI
Bacterial Contingency Loci: The Role of Simple Sequence DNA Repeats in Bacterial Adaptation
TL;DR: How bacterial pathogens exploit localized hypermutation, through polymerase slippage of simple sequence repeats (SSRs), to generate phenotypic variation and enhanced fitness is reviewed.
Journal ArticleDOI
Microbiology in the post-genomic era
Duccio Medini,Davide Serruto,Davide Serruto,Julian Parkhill,David A. Relman,Claudio Donati,Richard Moxon,Stanley Falkow,Rino Rappuoli +8 more
TL;DR: The evolving field of bacterial typing and the genomic technologies that enable comparative analysis of multiple genomes and the metagenomes of complex microbial environments are reviewed, and the implications of the genomic era for the future of microbiology are addressed.
Journal ArticleDOI
Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans
Davide Serruto,Tiziana Spadafina,Laura Ciucchi,Lisa A. Lewis,Sanjay Ram,Marta Tontini,Laura Santini,Alessia Biolchi,Kate L. Seib,Marzia Monica Giuliani,John J. Donnelly,Francesco Berti,Silvana Savino,Maria Scarselli,Paolo Costantino,J. Simon Kroll,Clíona A. O'Dwyer,Jiazhou Qiu,Andrew G. Plaut,Richard Moxon,Rino Rappuoli,Mariagrazia Pizza,Beatrice Aricò +22 more
TL;DR: It is shown that GNA2132 induces protective immunity in humans and it is recognized by sera of patients after meningococcal disease, and the protein binds heparin in vitro through an Arg-rich region and this property correlates with increased survival of the unencapped bacterium in human serum.
Journal ArticleDOI
Sialic acid transport in Haemophilus influenzae is essential for lipopolysaccharide sialylation and serum resistance and is dependent on a novel tripartite ATP‐independent periplasmic transporter
Emmanuele Severi,Gaynor Randle,Polly Kivlin,Kate Whitfield,Rosie Young,Richard Moxon,David J. Kelly,Derek W. Hood,Gavin H. Thomas +8 more
TL;DR: It is demonstrated that N‐acetylneuraminic acid (Neu5Ac or sialic acid) uptake in H.’influenzae is essential for the subsequent modification of the LPS and that this uptake is mediated through a single transport system which is a member of the tripartite ATP‐independent periplasmic (TRAP) transporter family.