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Natalia Maltsev
Researcher at University of Chicago
Publications - 58
Citations - 5058
Natalia Maltsev is an academic researcher from University of Chicago. The author has contributed to research in topics: Grid computing & BioPAX : Biological Pathways Exchange. The author has an hindex of 23, co-authored 58 publications receiving 4849 citations. Previous affiliations of Natalia Maltsev include Argonne National Laboratory & University of Illinois at Chicago.
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Journal ArticleDOI
The use of gene clusters to infer functional coupling
TL;DR: The characterization of the parameters that determine the utility of the approach are extended, and it is shown that this approach will play a significant role in supporting efforts to assign functionality to the remaining uncharacterized genes in sequenced genomes.
Journal ArticleDOI
The minimum information about a genome sequence (MIGS) specification.
Dawn Field,George M. Garrity,Tanya Gray,Norman Morrison,Jeremy D. Selengut,Peter Sterk,Tatiana Tatusova,Nicholas R. Thomson,Michael J. Allen,Samuel V. Angiuoli,Michael Ashburner,Nelson Axelrod,Sandra L. Baldauf,S. Ballard,Jeffrey L. Boore,Guy Cochrane,James R. Cole,Peter Dawyndt,Paul De Vos,Claude W. dePamphilis,Robert Edwards,Nadeem Faruque,Robert G. Feldman,Jack A. Gilbert,Paul Gilna,Frank Oliver Glöckner,Philip Goldstein,Robert P. Guralnick,Daniel H. Haft,David Hancock,Henning Hermjakob,Christiane Hertz-Fowler,Phil Hugenholtz,Ian Joint,Leonid Kagan,Matthew D. Kane,Jessie Kennedy,George A. Kowalchuk,Renzo Kottmann,Eugene Kolker,Saul A. Kravitz,Nikos C. Kyrpides,Jim Leebens-Mack,Suzanna E. Lewis,Kelvin Li,Allyson L. Lister,Phillip Lord,Natalia Maltsev,Victor Markowitz,Jennifer B. H. Martiny,Barbara A. Methé,Ilene Mizrachi,Richard Moxon,Karen E. Nelson,Julian Parkhill,Lita M. Proctor,Owen White,Susanna-Assunta Sansone,Andrew J. Spiers,Robert Stevens,Paul Swift,Chris F. Taylor,Yoshio Tateno,Adrian Tett,Sarah L. Turner,David W. Ussery,Bob Vaughan,Naomi L. Ward,Trish Whetzel,Ingio San Gil,Gareth A. Wilson,Anil Wipat +71 more
TL;DR: Here, the minimum information about a genome sequence (MIGS) specification is introduced with the intent of promoting participation in its development and discussing the resources that will be required to develop improved mechanisms of metadata capture and exchange.
Journal ArticleDOI
The BioPAX community standard for pathway data sharing
Emek Demir,Emek Demir,Michael P. Cary,Suzanne M. Paley,Ken Fukuda,Christian Lemer,Imre Vastrik,Guanming Wu,Peter D'Eustachio,Carl F. Schaefer,Joanne S. Luciano,Frank Schacherer,Irma Martínez-Flores,Zhenjun Hu,Verónica Jiménez-Jacinto,Geeta Joshi-Tope,Kumaran Kandasamy,Alejandra López-Fuentes,Huaiyu Mi,Elgar Pichler,Igor Rodchenkov,Andrea Splendiani,Andrea Splendiani,Sasha Tkachev,Jeremy Zucker,Gopal R. Gopinath,Harsha Rajasimha,Harsha Rajasimha,Ranjani Ramakrishnan,Imran Shah,Mustafa H Syed,Nadia Anwar,Özgün Babur,Özgün Babur,Michael L. Blinov,Erik Brauner,Dan Corwin,Sylva L. Donaldson,Frank Gibbons,Robert N. Goldberg,Peter Hornbeck,Augustin Luna,Peter Murray-Rust,Eric K. Neumann,Oliver Reubenacker,Matthias Samwald,Matthias Samwald,Martijn P. van Iersel,Sarala M. Wimalaratne,Keith Allen,Burk Braun,Michelle Whirl-Carrillo,Kei-Hoi Cheung,Kam D. Dahlquist,Andrew Finney,Marc Gillespie,Elizabeth M. Glass,Li Gong,Robin Haw,Michael Honig,Olivier Hubaut,David W. Kane,Shiva Krupa,Martina Kutmon,Julie Leonard,Debbie Marks,David Merberg,Victoria Petri,Alexander R. Pico,Dean Ravenscroft,Liya Ren,Nigam H. Shah,Margot Sunshine,Rebecca Tang,Ryan Whaley,Stan Letovksy,Kenneth H. Buetow,Andrey Rzhetsky,Vincent Schächter,Bruno S. Sobral,Ugur Dogrusoz,Shannon K. McWeeney,Mirit I. Aladjem,Ewan Birney,Julio Collado-Vides,Susumu Goto,Michael Hucka,Nicolas Le Novère,Natalia Maltsev,Akhilesh Pandey,Paul Thomas,Edgar Wingender,Peter D. Karp,Chris Sander,Gary D. Bader +94 more
TL;DR: Thousands of interactions, organized into thousands of pathways, from many organisms are available from a growing number of databases, and this large amount of pathway data in a computable form will support visualization, analysis and biological discovery.
Journal ArticleDOI
WIT: integrated system for high-throughput genome sequence analysis and metabolic reconstruction
Ross Overbeek,Niels Larsen,Gordon D. Pusch,Mark D'Souza,Evgeni Selkov,Nikos C. Kyrpides,Michael Fonstein,Natalia Maltsev +7 more
TL;DR: The WIT (What Is There) system has been designed to support comparative analysis of sequenced genomes and to generate metabolic reconstructions based on chromosomal sequences and metabolic modules from the EMP/MPW family of databases.
Journal Article
Use of contiguity on the chromosome to predict functional coupling.
TL;DR: A technique for detecting possible functional coupling between genes based on detection of potential operons, which has revealed a surprisingly rich and apparently accurate set of functionally coupled genes.