Robert Egan

TL;DR: The Critical Assessment of Metagenome Interpretation (CAMI) challenge has engaged the global developer community to benchmark their programs on highly complex and realistic data sets, generated from ∼700 newly sequenced microorganisms and ∼600 novel viruses and plasmids and representing common experimental setups as discussed by the authors.

TL;DR: A comparison of shotgun metagenome sequencing and assembly metrics of a defined microbial mock community using the Oxford Nanopore Technologies (ONT) MinION, PacBio and Illumina sequencing platforms is reported.

TL;DR: Benchmark metagenomes were generated from ~700 newly sequenced microorganisms and ~600 novel viruses and plasmids, including genomes with varying degrees of relatedness to each other and to publicly available ones and representing common experimental setups.

TL;DR: In this paper, a fast photochemical oxidation of proteins (FPOP) was used to perform HRPF in their laboratory on a very short time scale, which is a powerful and flexible technique for probing changes in protein topography.

TL;DR: In this paper, a flash photo-oxidation device and higher-order structural analysis (HOS) is employed for higher order structural analysis of biomolecules, which results from the confounded superimposition of a biomolecule's secondary, tertiary, and quaternary structure.