R
Roland E. Schmieder
Researcher at University of Erlangen-Nuremberg
Publications - 780
Citations - 85811
Roland E. Schmieder is an academic researcher from University of Erlangen-Nuremberg. The author has contributed to research in topics: Blood pressure & Essential hypertension. The author has an hindex of 97, co-authored 717 publications receiving 78138 citations. Previous affiliations of Roland E. Schmieder include Complutense University of Madrid & University of Regensburg.
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Journal ArticleDOI
Renin-angiotensin system and cardiovascular risk
TL;DR: Blockade of the renin-angiotensin system blockade delays or avoids the onset of type 2 diabetes and prevents cardiovascular and renal events in diabetic patients, and will remain a cornerstone of strategies to reduce cardiovascular risk.
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2018 Practice Guidelines for the management of arterial hypertension of the European Society of Hypertension and the European Society of Cardiology: ESH/ESC Task Force for the Management of Arterial Hypertension
Bryan Williams,Giuseppe Mancia,Wilko Spiering,Enrico Agabiti Rosei,Michel Azizi,Michel Burnier,Denis Clement,Antonio Coca,Giovanni de Simone,Anna F. Dominiczak,Thomas Kahan,Felix Mahfoud,Josep Redon,Luis M. Ruilope,Alberto Zanchetti,Mary Kerins,Sverre E. Kjeldsen,Reinhold Kreutz,Stéphane Laurent,Gregory Y.H. Lip,Richard J McManus,Krzysztof Narkiewicz,Frank Ruschitzka,Roland E. Schmieder,Evgeny Shlyakhto,Konstantinos Tsioufis,Victor Aboyans,Ileana Desormais +27 more
Journal ArticleDOI
Preeclampsia — A State of Sympathetic Overactivity
TL;DR: Preeclampsia is a state of sympathetic overactivity, which reverts to normal after delivery, which indicates that the increases in peripheral vascular resistance and blood pressure that characterize this disorder are mediated, at least in part, by a substantial increase in sympathetic vasoconstrictor activity.
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Catheter-based renal denervation in patients with uncontrolled hypertension in the absence of antihypertensive medications (SPYRAL HTN-OFF MED): a randomised, sham-controlled, proof-of-concept trial
Raymond R. Townsend,Felix Mahfoud,Felix Mahfoud,David E. Kandzari,Kazuomi Kario,Stuart J. Pocock,Michael A. Weber,Sebastian Ewen,Konstantinos Tsioufis,Dimitrios Tousoulis,Andrew S.P. Sharp,A. Watkinson,Roland E. Schmieder,Axel Schmid,James W. Choi,Cara East,Anthony Walton,Ingrid Hopper,Debbie L. Cohen,Robert L. Wilensky,David P. Lee,Adrian Ma,Chandan Devireddy,Janice P. Lea,Philipp Lurz,Karl Fengler,Justin E. Davies,Neil Chapman,Sidney Cohen,Vanessa DeBruin,Martin Fahy,Denise E Jones,Martin T. Rothman,Michael Böhm,Jiro Aoki,Bryan Batson,George Dangas,Shukri David,David E. Kandzari,Manesh R. Patel,Kiritkumar Patel,Jasvindar Singh,Thomas Weber,Joachim Weil,Thomas Zeller,Khaled M. Ziada,Kengo Tanabe,Robert Wilkins,Johanna Contreras,Susan Steigerwalt,Denise Reedus,Satoshi Hoshide,Laura P. Svetkey,Anjani Rao,Angela L. Brown,Markus Suppan,Tolga Agdirlioglu,Elias Noory,Craig Chasen +58 more
TL;DR: Results from SPYRAL HTN-OFF MED provide biological proof of principle for the blood-pressure-lowering efficacy of renal denervation in the absence of antihypertensive medications.
Journal ArticleDOI
Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of-concept randomised trial
David E. Kandzari,Michael Böhm,Felix Mahfoud,Felix Mahfoud,Raymond R. Townsend,Michael A. Weber,Stuart J. Pocock,Konstantinos Tsioufis,Dimitrios Tousoulis,James W. Choi,Cara East,Sandeep Brar,Sidney Cohen,Martin Fahy,Garrett Pilcher,Kazuomi Kario,Jiro Aoki,Bryan Batson,Debbie L. Cohen,George Dangas,Shukri David,Justin E. Davies,Chandan Devireddy,David E. Kandzari,David P. Lee,Philipp Lurz,Vasilios Papademetriou,Manesh R. Patel,Kiritkumar Patel,Roland E. Schmieder,Andrew S.P. Sharp,Jasvindar Singh,Antony Walton,Thomas Weber,Joachim Weil,Thomas Zeller,Khaled M. Ziada,Kengo Tanabe,Robert Wilkins,Robert L. Wilensky,Johanna Contreras,Susan Steigerwalt,Neil Chapman,Janice P. Lea,Denise Reedus,Satoshi Hoshide,Adrian Ma,Karl Fengler,Ping Li,Laura P. Svetkey,Anjani Rao,Axel Schmid,A. Watkinson,Angela L. Brown,Ingrid Hopper,Markus Suppan,Tolga Agdirlioglu,Elias Noory,Craig Chasen +58 more
TL;DR: Renal denervation in the main renal arteries and branches significantly reduced blood pressure compared with sham control with no major safety events.