Roland E. Schmieder

TL;DR: Despite different changes of systemic haemodynamics between CVVH and IHD,CVVH did not improve parameters of splanchnic regional perfusion like pHi, pCO(2)i or pCO (2) gap in septic shock patients.

TL;DR: Cuff BP has variable accuracy for measuring either brachial or aortic intra-arterial BP, and this adversely influences correct BP classification, indicating that stronger accuracy standards for BP devices may improve cardiovascular risk management.

TL;DR: Clinical evidence in support of RDN as an effective interventional technique in patients with resistant hypertension is conflicting; a number of observational studies and three randomized, controlled trials support both safety and efficacy of this new therapy but some smaller studies and the large, single-blind, randomized, sham-controlled symplicity HTN-3 trial failed to show superiority ofRDN when compared with medical therapy alone.

TL;DR: Overall, CV protection was favorably affected by the less tight but not by the tighter BP target, and the more frequent achievement of the BP targets led to cerebrovascular and renal protection, but did not increase cardiac protection.

TL;DR: Dietary salt intake reduction can delay or prevent the incidence of antihypertensive therapy, can facilitate blood pressure reduction in hypertensive patients receiving medical therapy, and may represent a simple cost-saving mediator to reduce cardiovascular morbidity and mortality.