S
Scott M. Grundy
Researcher at University of Texas Southwestern Medical Center
Publications - 849
Citations - 246629
Scott M. Grundy is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Cholesterol & Lipoprotein. The author has an hindex of 187, co-authored 841 publications receiving 231821 citations. Previous affiliations of Scott M. Grundy include University of California, San Francisco & University of California, Davis.
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Journal ArticleDOI
Role of Genetic Polymorphism Peroxisome Proliferator–Activated Receptor-γ2 Pro12Ala on Ethnic Susceptibility to Diabetes in South-Asian and Caucasian Subjects: Evidence for heterogeneity
Venkatesan Radha,Karani Santhanakrishnan Vimaleswaran,Hunsur Narayan Sathish Babu,Nicola Abate,Manisha Chandalia,Pankaj Satija,Scott M. Grundy,Saurabh Ghosh,Partha P. Majumder,Raj Deepa,Sathyanarayana M R Rao,Viswanathan Mohan +11 more
TL;DR: This study supports the hypothesis that the PPAR-gamma Pro12Ala polymorphism is protective against diabetes in Caucasians but not in South Asians.
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Inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase by mevinolin in familial hypercholesterolemia heterozygotes: effects on cholesterol balance.
TL;DR: It is concluded that the LDL lowering action of mevinolin does not appear to require a severe decrease in cholesterol synthesis that might lead to depletion of vital body stores of cholesterol.
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Approach to lipoprotein management in 2001 National Cholesterol Guidelines
TL;DR: In 2001 the National Cholesterol Education Program (NCEP) released its ATP III report, an evidence-based report that upgraded cholesterol management guidelines and placed more emphasis on the metabolic syndrome as a major, multiplex risk factor requiring increased clinical attention.
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Prevention Conference V Beyond Secondary Prevention : Identifying the High-Risk Patient for Primary Prevention : Medical Office Assessment : Writing Group I
Scott M. Grundy,Terry L. Bazzarre,James I. Cleeman,Ralph B. D'Agostino,Martha N. Hill,Nancy Houston-Miller,William B. Kannel,Ronald M. Krauss,Harlan M. Krumholz,Ronald M. Lauer,Ira S. Ockene,Richard C. Pasternak,Thomas A. Pearson,Paul M. Ridker,Darien Wood +14 more
TL;DR: The role of medical office assessment in the detection of risk factors and estimation of total cardiovascular risk was reviewed, with a primary focus on identification of known risk factors for coronary heart disease (CHD).
Journal ArticleDOI
Intestinal absorption of polyenephosphatidylcholine in man
O. Zierenberg,Scott M. Grundy +1 more
TL;DR: Examination of lipoproteins revealed that the specific activity of PC in high density lipoprotein (HDL) was 2 to 6 times higher than in apoB-containing lipoproduins, and to 2 to 20 times than that of red blood cells or total blood, suggesting that absorbed PC seemingly was incorporated preferentially into the HDL fraction of plasma.