S
Scott M. Grundy
Researcher at University of Texas Southwestern Medical Center
Publications - 849
Citations - 246629
Scott M. Grundy is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Cholesterol & Lipoprotein. The author has an hindex of 187, co-authored 841 publications receiving 231821 citations. Previous affiliations of Scott M. Grundy include University of California, San Francisco & University of California, Davis.
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Journal ArticleDOI
The effect of treatment with clofibrate on hepatic triglyceride and lipoprotein lipase activities of post heparin plasma in male patients with hyperlipoproteinemia.
TL;DR: The possibility that the serum triglyceride-lowering effect of clofibrate might partly be explained by an increased removal rate of triglyceride rich lipoproteins through increased lipoprotein lipase activity is discussed.
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Problems on the pathway from risk assessment to risk reduction
TL;DR: periodic measurement of CVD risk factors in healthy people (step 1) is routinely recommended by the AHA, the ACC, and the NHLBI, in addition to other authorities on disease prevention.
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Bimodal Distribution of Cholesteryl Ester Transfer Protein Activities in Normotriglyceridemic Men With Low HDL Cholesterol Concentrations
TL;DR: Elevated CETP activity may be a significant factor in causing low HDL cholesterol levels in a distinct subgroup of normolipidemic patients with low HDLolesterol levels, and postheparin plasma activities of lipoprotein lipase (LPL) and hepatic triglyceridelipase (HTGL) were determined in 71 patients with a high HDL cholesterol level.
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Serum insulin and inflammatory markers in overweight individuals with and without dyslipidemia.
Philip J. Barter,Y. Ruth McPherson,Kijoung Song,Y. Antero Kesäniemi,Robert W. Mahley,Gérard Waeber,Thomas P. Bersot,Vincent Mooser,Dawn M. Waterworth,Scott M. Grundy +9 more
TL;DR: Identification of people solely on the basis of an elevated plasma triglyceride and a low HDL-C uncovers an overweight group of people who have a generalized metabolic disorder, which may be at relatively low risk of developing diabetes and cardiovascular disease despite being overweight.
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Studies on the metabolism of apolipoprotein B in hypertriglyceridemic subjects using simultaneous administration of tritiated leucine and radioiodinated very low density lipoprotein.
TL;DR: The wide spectrum of this loss pathway indicates that previous estimates of VLDL apoB production rate using the radioiodinated methodology probably represent lower bounds for the true physiologic variable.