S
Sophie Hue
Researcher at University of Paris
Publications - 82
Citations - 3683
Sophie Hue is an academic researcher from University of Paris. The author has contributed to research in topics: COPD & Cytotoxic T cell. The author has an hindex of 27, co-authored 82 publications receiving 2832 citations. Previous affiliations of Sophie Hue include University of Paris-Est & Necker-Enfants Malades Hospital.
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Journal ArticleDOI
A Direct Role for NKG2D/MICA Interaction in Villous Atrophy during Celiac Disease
Sophie Hue,Jean-Jacques Mention,Renato C. Monteiro,Shao Ling Zhang,Christophe Cellier,Jacques Schmitz,Virginie Verkarre,Nassima Fodil,Seiamak Bahram,Nadine Cerf-Bensussan,Sophie Caillat-Zucman +10 more
TL;DR: It is shown that MICA is strongly expressed at epithelial cell surface in patients with active disease and is induced by gliadin or its p31-49 derived peptide upon in vitro challenge, which supports a key role for MIC/NKG2D in the activation of intraepithelial immunity in response to danger.
Journal ArticleDOI
Maturation and persistence of the anti-SARS-CoV-2 memory B cell response.
Aurélien Sokal,Pascal Chappert,Giovanna Barba-Spaeth,Anaïs Roeser,Slim Fourati,Imane Azzaoui,Alexis Vandenberghe,Ignacio Fernandez,Annalisa Meola,Magali Bouvier-Alias,Etienne Crickx,Asma Beldi-Ferchiou,Sophie Hue,Laetitia Languille,Marc Michel,Samia Baloul,Marine Luka,Marine Luka,Jérôme Mégret,Mickaël M. Ménager,Mickaël M. Ménager,Jean-Michel Pawlotsky,Simon Fillatreau,Félix A. Rey,Jean-Claude Weill,Claude-Agnès Reynaud,Matthieu Mahévas +26 more
TL;DR: In this paper, a longitudinal single-cell and repertoire profiling of the B cell response up to 6 months in mild and severe COVID-19 patients was performed, showing that an antigen-driven activation persisted and matured up to six months after SARS-CoV-2 infection and may provide longterm protection.
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Telomere Dysfunction Causes Sustained Inflammation in Chronic Obstructive Pulmonary Disease
Amsellem,Guillaume Gary-Bobo,Elisabeth Marcos,Bernard Maitre,Chaar,Pierre Validire,Jean-Baptiste Stern,Hiba Noureddine,Sapin E,Dominique Rideau,Sophie Hue,Le Corvoisier P,Le Gouvello S,Jean-Luc Dubois-Randé,Jorge Boczkowski,Serge Adnot +15 more
TL;DR: Telomere dysfunction and premature P-EC senescence are major processes perpetuating lung inflammation in COPD.
Journal ArticleDOI
Comparative analysis of human NK cell activation induced by NKG2D and natural cytotoxicity receptors
Pascale Andre,Roberta Castriconi,Marion Espéli,Nicolas Anfossi,Tiffany Juarez,Sophie Hue,Holli Conway,François Romagné,Alessandra Dondero,Marina Nanni,Sophie Caillat-Zucman,David H. Raulet,Cristina Bottino,Eric Vivier,Alessandro Moretta,Pascale Paul +15 more
TL;DR: Data show that target recognition via NKG2D or NCR triggers all aspects of NK activation, and pave the way for further dissection of the signaling pathways induced by NK cell recognition of ULBP‐1 and MICA.
Journal ArticleDOI
CD39/Adenosine Pathway Is Involved in AIDS Progression
Maria Nikolova,Matthieu Carrière,Mohammad-Ali Jenabian,Sophie Limou,Sophie Limou,Mehwish Younas,Ayrin Kök,Sophie Hue,Nabila Seddiki,Anne Hulin,Olivier Delaneau,Hanneke Schuitemaker,Joshua T. Herbeck,James I. Mullins,Maria Muhtarova,Armand Bensussan,Jean-François Zagury,Jean-François Zagury,Jean-Daniel Lelièvre,Jean-Daniel Lelièvre,Yves Levy,Yves Levy +21 more
TL;DR: It is shown in vitro that the CD39/adenosine axis is involved in Treg suppression in HIV infection and a genetic association study identified a CD39 gene polymorphism that was associated with down-modulated CD39 expression and a slower progression to AIDS.