M
Manuel Sanchez
Researcher at University of Zaragoza
Publications - 5
Citations - 2650
Manuel Sanchez is an academic researcher from University of Zaragoza. The author has contributed to research in topics: Genome-wide association study & Cancer. The author has an hindex of 5, co-authored 5 publications receiving 2505 citations.
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Journal ArticleDOI
Erratum: Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer (Nature Genetics (2009) 41 (991-995))
Xifeng Wu,Yuanqing Ye,Lambertus A. Kiemeney,Patrick Sulem,Thorunn Rafnar,Giuseppe Matullo,Daniela Seminara,Teruhiko Yoshida,Norihisa Saeki,Angeline S. Andrew,Colin P.N. Dinney,Bogdan Czerniak,Zuo-Feng Zhang,Anne E. Kiltie,D. Timothy Bishop,Paolo Vineis,Stefano Porru,Frank Buntinx,Eliane Kellen,Maurice P. Zeegers,Rajesh Kumar,Peter Rudnai,Eugene Gurzau,Kvetoslava Koppova,Jose I. Mayordomo,Manuel Sanchez,Berta Saez,Annika Lindblom,Petra J. de Verdier,Gunnar Steineck,Gordon B. Mills,Alan R. Schned,Shen Chih Chang,Jie Lin,David W. Chang,Katherine S. Hale,Tadeusz Majewski,H. Barton Grossman,Steinunn Thorlacius,Unnur Thorsteinsdottir,Katja K.H. Aben,J. Alfred Witjes,Kari Stefansson,Christopher I. Amos,Margaret R. Karagas,Jian Gu +45 more
TL;DR: In the version of this article initially published online, Simonetta Guarrera and Silvia Polidoro were inadvertently omitted from the author list, and an affiliation was omitted for Paolo Vineis as mentioned in this paper.
Journal ArticleDOI
A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci
Nathaniel Rothman,Montserrat Garcia-Closas,Nilanjan Chatterjee,Núria Malats,Xifeng Wu,Jonine D. Figueroa,Francisco X. Real,David Van Den Berg,Giuseppe Matullo,Dalsu Baris,Michael J. Thun,Lambertus A. Kiemeney,Paolo Vineis,Immaculata De Vivo,Demetrius Albanes,Mark P. Purdue,Thorunn Rafnar,Michelle A.T. Hildebrandt,Anne E. Kiltie,Olivier Cussenot,Klaus Golka,Rajesh Kumar,Jack A. Taylor,Jose I. Mayordomo,Kevin B. Jacobs,Manolis Kogevinas,Amy Hutchinson,Zhaoming Wang,Yi-Ping Fu,Ludmila Prokunina-Olsson,Laurie Burdett,Meredith Yeager,William Wheeler,Adonina Tardón,Consol Serra,Alfredo Carrato,Reina García-Closas,Josep Lloreta,Alison Johnson,Molly Schwenn,Margaret R. Karagas,Alan R. Schned,Gerald L. Andriole,Robert L. Grubb,Amanda Black,Eric J. Jacobs,W. Ryan Diver,Susan M. Gapstur,Stephanie J. Weinstein,Jarmo Virtamo,Victoria K. Cortessis,Manuela Gago-Dominguez,Malcolm C. Pike,Malcolm C. Pike,Mariana C. Stern,Jian-Min Yuan,David J. Hunter,Monica McGrath,Colin P.N. Dinney,Bogdan Czerniak,Meng Chen,Hushan Yang,Sita H. Vermeulen,Katja K.H. Aben,J. Alfred Witjes,Remco R. R. Makkinje,Patrick Sulem,Søren Besenbacher,Kari Stefansson,Kari Stefansson,Elio Riboli,Paul Brennan,Salvatore Panico,Carmen Navarro,Naomi E. Allen,H. Bas Bueno-de-Mesquita,Dimitrios Trichopoulos,Dimitrios Trichopoulos,Neil E. Caporaso,Maria Teresa Landi,Federico Canzian,Börje Ljungberg,Anne Tjønneland,Françoise Clavel-Chapelon,D T Bishop,Mark Teo,Margaret A. Knowles,Simonetta Guarrera,Silvia Polidoro,Fulvio Ricceri,Carlotta Sacerdote,Alessandra Allione,Geraldine Cancel-Tassin,Silvia Selinski,Jan G. Hengstler,Holger Dietrich,Tony Fletcher,Peter Rudnai,Eugen Gurzau,Kvetoslava Koppova,Sophia C.E. Bolick,Ashley C. Godfrey,Zongli Xu,José I Sanz-Velez,Maria D. Garcia-Prats,Manuel Sanchez,Gabriel Valdivia,Stefano Porru,Simone Benhamou,Simone Benhamou,Robert N. Hoover,Joseph F. Fraumeni,Debra T. Silverman,Stephen J. Chanock +113 more
TL;DR: Two new regions associated with bladder cancer on chromosomes 22q13.1, 19q12 and 2q37.1 are identified and previous candidate associations for the GSTM1 deletion and a tag SNP for NAT2 acetylation status are validated, and interactions with smoking in both regions are found.
Journal ArticleDOI
Sequence Variant on 8q24 Confers Susceptibility to Urinary Bladder Cancer
Lambertus A. Kiemeney,Steinunn Thorlacius,Patrick Sulem,Frank Geller,Katja K H Aben,Simon N. Stacey,Julius Gudmundsson,Margret Jakobsdottir,Jon Thor Bergthorsson,Asgeir Sigurdsson,Thorarinn Blondal,J. Alfred Witjes,Sita H. Vermeulen,Christina A. Hulsbergen-van de Kaa,Dorine W. Swinkels,Martine Ploeg,Erik B. Cornel,Henk Vergunst,Thorgeir E. Thorgeirsson,Daniel F. Gudbjartsson,Sigurjon A. Gudjonsson,Gudmar Thorleifsson,Kari T. Kristinsson,Magali Mouy,Steinunn Snorradottir,Donatella Placidi,Marcello Campagna,Cecilia Arici,Kvetoslava Koppova,Eugene Gurzau,Peter Rudnai,Eliane Kellen,Silvia Polidoro,Simonetta Guarrera,Carlotta Sacerdote,Manuel Sanchez,Berta Saez,Gabriel Valdivia,Charlotta Ryk,Petra J. de Verdier,Annika Lindblom,Klaus Golka,D. Timothy Bishop,Margaret A. Knowles,Sigfus Nikulasson,Vigdis Petursdottir,Eirikur Jonsson,Gudmundur Geirsson,Baldvin Kristjansson,Jose I. Mayordomo,Gunnar Steineck,Stefano Porru,Frank Buntinx,Frank Buntinx,Maurice P. Zeegers,Maurice P. Zeegers,Tony Fletcher,Rajesh Kumar,Giuseppe Matullo,Paolo Vineis,Anne E. Kiltie,Jeffrey R. Gulcher,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Augustine Kong,Thorunn Rafnar,Kari Stefansson,Kari Stefansson +67 more
TL;DR: No association was observed between UBC and the four 8q24 variants previously associated with prostate, colorectal and breast cancers, nor did rs9642880 associate with any of these three cancers.
Journal ArticleDOI
Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer
Xifeng Wu,Yuanqing Ye,Lambertus A. Kiemeney,Patrick Sulem,Thorunn Rafnar,Giuseppe Matullo,Daniela Seminara,Teruhiko Yoshida,Norihisa Saeki,Angeline S. Andrew,Colin P.N. Dinney,Bogdan Czerniak,Zuo-Feng Zhang,Anne E. Kiltie,D. Timothy Bishop,Paolo Vineis,Stefano Porru,Frank Buntinx,Frank Buntinx,E Kellen,E Kellen,Maurice P. Zeegers,Maurice P. Zeegers,Rajesh Kumar,Peter Rudnai,Eugene Gurzau,Kvetoslava Koppova,Jose I. Mayordomo,Manuel Sanchez,Berta Saez,Annika Lindblom,Petra J. de Verdier,Gunnar Steineck,Gordon B. Mills,Alan R. Schned,Simonetta Guarrera,Silvia Polidoro,Shen Chih Chang,Jie Lin,David W. Chang,Katherine S. Hale,Tadeusz Majewski,H. Barton Grossman,Steinunn Thorlacius,Unnur Thorsteinsdottir,Katja K.H. Aben,J. Alfred Witjes,Kari Stefansson,Christopher I. Amos,Margaret R. Karagas,Jian Gu +50 more
TL;DR: A missense variant (rs2294008) in the PSCA gene showed consistent association with bladder cancer in US and European populations and was identified as a new bladder cancer susceptibility locus.
Journal ArticleDOI
European genome-wide association study identifies SLC14A1 as a new urinary bladder cancer susceptibility gene
Thorunn Rafnar,Sita H. Vermeulen,Patrick Sulem,Gudmar Thorleifsson,Katja K.H. Aben,J. Alfred Witjes,Anne J. Grotenhuis,Gerald W. Verhaegh,Christina A. Hulsbergen-van de Kaa,Søren Besenbacher,Daniel F. Gudbjartsson,Simon N. Stacey,Julius Gudmundsson,Hrefna Johannsdottir,Hjordis Bjarnason,Carlo Zanon,Hafdis T. Helgadottir,Jon G. Jonasson,Laufey Tryggvadottir,Eirikur Jonsson,Gudmundur Geirsson,Sigfus Nikulasson,Vigdis Petursdottir,D. Timothy Bishop,Sei Chung-Sak,Ananya Choudhury,Faye Elliott,Jennifer H. Barrett,Margaret A. Knowles,Petra J. de Verdier,Charlotta Ryk,Annika Lindblom,Peter Rudnai,Eugene Gurzau,Kvetoslava Koppova,Paolo Vineis,Silvia Polidoro,Simonetta Guarrera,Carlotta Sacerdote,Angeles Panadero,José I Sanz-Velez,Manuel Sanchez,Gabriel Valdivia,Maria D. Garcia-Prats,Jan G. Hengstler,Silvia Selinski,Holger Gerullis,Daniel Ovsiannikov,Abdolaziz Khezri,Alireza Aminsharifi,Mahyar Malekzadeh,Leonard H. van den Berg,Roel A. Ophoff,Roel A. Ophoff,Jan H. Veldink,Maurice P. Zeegers,Eliane Kellen,Jacopo Fostinelli,Daniele Andreoli,Cecilia Arici,Stefano Porru,Frank Buntinx,Frank Buntinx,Abbas Ghaderi,Klaus Golka,Jose I. Mayordomo,Giuseppe Matullo,Rajesh Kumar,Gunnar Steineck,Anne E. Kiltie,Augustine Kong,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Kari Stefansson,Kari Stefansson,Lambertus A. Kiemeney +75 more
TL;DR: It is speculated that rs17674580, or other sequence variants in LD with it, indirectly modifies UBC risk by affecting urine production, which would support the 'urogenous contact hypothesis' that urine production and voiding frequency modify the risk of UBC.