S
Steven B. Bradfute
Researcher at University of New Mexico
Publications - 100
Citations - 6003
Steven B. Bradfute is an academic researcher from University of New Mexico. The author has contributed to research in topics: Ebola virus & Medicine. The author has an hindex of 29, co-authored 82 publications receiving 4927 citations. Previous affiliations of Steven B. Bradfute include United States Army Medical Research Institute of Infectious Diseases & United States Department of the Army.
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Journal ArticleDOI
Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarction
Hidemasa Oh,Steven B. Bradfute,Teresa D. Gallardo,Teruya Nakamura,Vinciane Gaussin,Yuji Mishina,Jennifer Pocius,Lloyd H. Michael,Richard R. Behringer,Daniel J. Garry,Mark L. Entman,Michael D. Schneider +11 more
TL;DR: The existence of adult heart-derived cardiac progenitor cells expressing stem cell antigen-1.5 is reported, and differentiation was shown to occur roughly equally, with and without fusion to host cells.
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TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome Maturation
Manohar Pilli,John Arko-Mensah,Marisa Ponpuak,Marisa Ponpuak,Esteban A. Roberts,Sharon Master,Michael A. Mandell,Nicolas Dupont,Wojciech Ornatowski,Shanya Jiang,Steven B. Bradfute,Jack-Ansgar Bruun,Tom Egil Hansen,Terje Johansen,Vojo Deretic +14 more
TL;DR: TBK-1 is a key regulator of immunological autophagy and is responsible for the maturation of autophagosomes into lytic bactericidal organelles.
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The value of antimicrobial peptides in the age of resistance
Maria Magana,Muthuirulan Pushpanathan,Ana L. Santos,Leon G. Leanse,Michael Fernandez,Anastasios Ioannidis,Marc A. Giulianotti,Yiorgos Apidianakis,Steven B. Bradfute,Andrew L. Ferguson,Artem Cherkasov,Mohamed N. Seleem,Clemencia Pinilla,Cesar de la Fuente-Nunez,Themis Lazaridis,Themis Lazaridis,Tianhong Dai,Richard A. Houghten,Robert E. W. Hancock,George P. Tegos +19 more
TL;DR: The benefits, challenges, and opportunities of using antimicrobial peptides against multidrug-resistant pathogens are identified, advances in the deployment of novel promising antimacterial peptides are highlighted, and the needs and priorities in designing focused development strategies taking into account the most advanced tools available are underlined.
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Hematopoietic Fingerprints: an expression database of stem cells and their progeny
Stuart M. Chambers,Nathan C. Boles,Kuan Yin K. Lin,Megan P. Tierney,Teresa V. Bowman,Steven B. Bradfute,Alice J. Chen,Akil Merchant,Olga Sirin,David C. Weksberg,Mehveen G. Merchant,C. Joseph Fisk,Chad A. Shaw,Margaret A. Goodell +13 more
TL;DR: An expression database of hematopoietic stem cells and their differentiated progeny was generated and approximately 100-400 genes uniquely expressed in each cell type were identified, termed lineage "fingerprints," demonstrating the utility of the fingerprints for identifying genes that regulate differentiation.
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Ebola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machinery.
Tsung-Hsien Chang,Toru Kubota,Mayumi Matsuoka,Steven M. Jones,Steven B. Bradfute,Mike Bray,Keiko Ozato +6 more
TL;DR: Findings indicate that Ebola Zaire virus exploits the cellular SUMOylation machinery for its advantage and help to explain how the virus overcomes host innate defenses, causing rapidly overwhelming infection to produce a syndrome resembling fulminant septic shock.