Susan M. Webb

TL;DR: In this article, a prospective, investigator-initiated, double blind, placebo-controlled, crossover study was conducted to assess whether weekly administration of 40 mg pegvisomant (PEG-V) improves quality of life (QoL) and metabolic parameters in acromegalic patients with normal age-adjusted IGF-I concentrations during long-acting SSA treatment.

TL;DR: Until refinements in technique occur, LOOP excision of the cervix during pregnancy does not consistently produce diagnostic specimens and is associated with a significant rate of residual disease.

TL;DR: In this article, the authors investigated the possible coexistence of pituitary adenoma and pheo/PGL and found that mutations in the genes known to cause PPGL can rarely be associated with pituitaries, whereas mutation in a gene predisposing to Pituitary Adenomas (MEN1) can be associated this article.

TL;DR: Despite long-term cure, patients who have suffered CS exhibit persistent accumulation of central fat, as in active hypercortisolemia, with the consequent unfavorable adipokine profile, leading to a state of low-grade inflammation.

TL;DR: Patients with active CS demonstrate brain abnormalities, which only partly recover after biochemical cure, because these still occur even after long-term remission, according to a systematic review of publications evaluating brain characteristics in patients with CS using magnetic resonance imaging (MRI).