S
Swagatika Sahoo
Researcher at University of Luxembourg
Publications - 17
Citations - 2372
Swagatika Sahoo is an academic researcher from University of Luxembourg. The author has contributed to research in topics: Metabolic network & Gut flora. The author has an hindex of 10, co-authored 17 publications receiving 1861 citations. Previous affiliations of Swagatika Sahoo include Indian Institute of Technology Madras & University of Iceland.
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Journal ArticleDOI
A community-driven global reconstruction of human metabolism
Ines Thiele,Neil Swainston,Ronan M. T. Fleming,Andreas Hoppe,Swagatika Sahoo,Maike K. Aurich,Hulda S. Haraldsdóttir,Monica L. Mo,Ottar Rolfsson,Miranda D. Stobbe,Miranda D. Stobbe,Stefan Gretar Thorleifsson,Rasmus Agren,Christian Bölling,Sergio Bordel,Arvind K. Chavali,Paul D. Dobson,Warwick B. Dunn,Warwick B. Dunn,Lukas Endler,David Hala,Michael Hucka,Duncan Hull,Daniel Jameson,Neema Jamshidi,Jon J. Jonsson,Nick Juty,Sarah M. Keating,Intawat Nookaew,Nicolas Le Novère,Nicolas Le Novère,Naglis Malys,Naglis Malys,Alexander Mazein,Jason A. Papin,Nathan D. Price,Evgeni Selkov,Martin I. Sigurdsson,Evangelos Simeonidis,Evangelos Simeonidis,Nikolaus Sonnenschein,Kieran Smallbone,Anatoly Sorokin,Anatoly Sorokin,Johannes H. G. M. van Beek,Dieter Weichart,Igor Goryanin,Jens Nielsen,Hans V. Westerhoff,Douglas B. Kell,Pedro Mendes,Pedro Mendes,Bernhard O. Palsson,Bernhard O. Palsson +53 more
TL;DR: Recon 2, a community-driven, consensus 'metabolic reconstruction', is described, which is the most comprehensive representation of human metabolism that is applicable to computational modeling and has improved topological and functional features.
Journal ArticleDOI
Recon3D enables a three-dimensional view of gene variation in human metabolism.
Elizabeth Brunk,Elizabeth Brunk,Swagatika Sahoo,Daniel C. Zielinski,Ali Altunkaya,Ali Altunkaya,Andreas Dräger,Nathan Mih,Francesco Gatto,Francesco Gatto,Avlant Nilsson,German Andres Preciat Gonzalez,Maike K. Aurich,Andreas Prlić,Anand V. Sastry,Anna Dröfn Daníelsdóttir,Almut Heinken,Alberto Noronha,Peter W. Rose,Stephen K. Burley,Stephen K. Burley,Ronan M. T. Fleming,Ronan M. T. Fleming,Jens Nielsen,Jens Nielsen,Ines Thiele,Bernhard O. Palsson,Bernhard O. Palsson +27 more
TL;DR: Recon3D is presented, a computational resource that includes three-dimensional metabolite and protein structure data and enables integrated analyses of metabolic functions in humans and is used to functionally characterize mutations associated with disease, and identify metabolic response signatures that are caused by exposure to certain drugs.
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The Virtual Metabolic Human database: integrating human and gut microbiome metabolism with nutrition and disease.
Alberto Noronha,Jennifer Modamio,Yohan Jarosz,Elisabeth Guerard,Nicolas Sompairac,German Andres Preciat Gonzalez,Anna Dröfn Daníelsdóttir,Max Krecke,Diane Merten,Hulda S. Haraldsdóttir,Almut Heinken,Laurent Heirendt,Stefania Magnusdottir,Dmitry A. Ravcheev,Swagatika Sahoo,Piotr Gawron,Lucia Friscioni,Beatriz Garcia,Mabel Prendergast,Alberto Puente,Mariana Rodrigues,Akansha Roy,Mouss Rouquaya,Luca Wiltgen,Alise Žagare,Elisabeth John,Maren Krueger,Inna Kuperstein,Andrei Zinovyev,Reinhard Schneider,Ronan M. T. Fleming,Ronan M. T. Fleming,Ines Thiele +32 more
TL;DR: The VMH represents a novel, interdisciplinary database for data interpretation and hypothesis generation to the biomedical community and encapsulating current knowledge of human metabolism within five interlinked resources.
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Systems-level characterization of a host-microbe metabolic symbiosis in the mammalian gut.
TL;DR: It is demonstrated in silico that the presence of B. thetaiotaomicron could rescue the growth phenotype of the host with an otherwise lethal enzymopathy and vice versa, and represents a powerful tool for modeling metabolic interactions between a gut microbe and its host in health and disease.
Journal ArticleDOI
Personalized whole-body models integrate metabolism, physiology, and the gut microbiome.
Ines Thiele,Swagatika Sahoo,Almut Heinken,Johannes Hertel,Johannes Hertel,Laurent Heirendt,Maike K. Aurich,Ronan M. T. Fleming,Ronan M. T. Fleming +8 more
TL;DR: A new metabolic network reconstruction approach that used organ‐specific information from literature and omics data to generate two sex‐specific whole‐body metabolic (WBM) reconstructions that capture the metabolism of 26 organs and six blood cell types is developed.