S
Sylke Winkler
Researcher at Max Planck Society
Publications - 54
Citations - 3644
Sylke Winkler is an academic researcher from Max Planck Society. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 19, co-authored 44 publications receiving 2036 citations. Previous affiliations of Sylke Winkler include Dresden University of Technology.
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Journal ArticleDOI
Towards complete and error-free genome assemblies of all vertebrate species
Arang Rhie,Shane A. McCarthy,Shane A. McCarthy,Olivier Fedrigo,Joana Damas,Giulio Formenti,Sergey Koren,Marcela Uliano-Silva,William Chow,Arkarachai Fungtammasan,J. H. Kim,Chul Hee Lee,Byung June Ko,Mark Chaisson,Gregory Gedman,Lindsey J. Cantin,Françoise Thibaud-Nissen,Leanne Haggerty,Iliana Bista,Iliana Bista,Michelle Smith,Bettina Haase,Jacquelyn Mountcastle,Sylke Winkler,Sylke Winkler,Sadye Paez,Jason T. Howard,Sonja C. Vernes,Sonja C. Vernes,Sonja C. Vernes,Tanya M. Lama,Frank Grützner,Wesley C. Warren,Christopher N. Balakrishnan,Dave W Burt,Jimin George,Matthew T. Biegler,David Iorns,Andrew Digby,Daryl Eason,Bruce C. Robertson,Taylor Edwards,Mark Wilkinson,George F. Turner,Axel Meyer,Andreas F. Kautt,Andreas F. Kautt,Paolo Franchini,H. William Detrich,Hannes Svardal,Hannes Svardal,Maximilian Wagner,Gavin J. P. Naylor,Martin Pippel,Milan Malinsky,Milan Malinsky,Mark Mooney,Maria Simbirsky,Brett T. Hannigan,Trevor Pesout,Marlys L. Houck,Ann C Misuraca,Sarah B. Kingan,Richard Hall,Zev N. Kronenberg,Ivan Sović,Christopher Dunn,Zemin Ning,Alex Hastie,Joyce V. Lee,Siddarth Selvaraj,Richard E. Green,Nicholas H. Putnam,Ivo Gut,Jay Ghurye,Erik Garrison,Ying Sims,Joanna Collins,Sarah Pelan,James Torrance,Alan Tracey,Jonathan Wood,Robel E. Dagnew,Dengfeng Guan,Dengfeng Guan,Sarah E. London,David F. Clayton,Claudio V. Mello,Samantha R. Friedrich,Peter V. Lovell,Ekaterina Osipova,Farooq O. Al-Ajli,Farooq O. Al-Ajli,Simona Secomandi,Heebal Kim,Constantina Theofanopoulou,Michael Hiller,Yang Zhou,Robert S. Harris,Kateryna D. Makova,Paul Medvedev,Jinna Hoffman,Patrick Masterson,Karen Clark,Fergal J. Martin,Kevin L. Howe,Paul Flicek,Brian P. Walenz,Woori Kwak,Hiram Clawson,Mark Diekhans,Luis R Nassar,Benedict Paten,Robert H. S. Kraus,Robert H. S. Kraus,Andrew J. Crawford,M. Thomas P. Gilbert,M. Thomas P. Gilbert,Guojie Zhang,Byrappa Venkatesh,Robert W. Murphy,Klaus-Peter Koepfli,Beth Shapiro,Beth Shapiro,Warren E. Johnson,Warren E. Johnson,Federica Di Palma,Tomas Marques-Bonet,Emma C. Teeling,Tandy Warnow,Jennifer A. Marshall Graves,Oliver A. Ryder,Oliver A. Ryder,David Haussler,Stephen J. O'Brien,Jonas Korlach,Harris A. Lewin,Kerstin Howe,Eugene W. Myers,Eugene W. Myers,Richard Durbin,Richard Durbin,Adam M. Phillippy,Erich D. Jarvis,Erich D. Jarvis +144 more
TL;DR: The Vertebrate Genomes Project (VGP) as mentioned in this paper is an international effort to generate high quality, complete reference genomes for all of the roughly 70,000 extant vertebrate species and to help to enable a new era of discovery across the life sciences.
Posted ContentDOI
Towards complete and error-free genome assemblies of all vertebrate species
Arang Rhie,Shane A. McCarthy,Olivier Fedrigo,Joana Damas,Giulio Formenti,Sergey Koren,Marcela Uliano-Silva,William Chow,Arkarachai Fungtammasan,Gregory Gedman,Lindsey J. Cantin,Françoise Thibaud-Nissen,Leanne Haggerty,Chul Hee Lee,Byung June Ko,J. H. Kim,Iliana Bista,Michelle Smith,Bettina Haase,Jacquelyn Mountcastle,Sylke Winkler,Sadye Paez,Jason T. Howard,Sonja C. Vernes,Tanya M. Lama,Frank Grützner,Wesley C. Warren,Christopher N. Balakrishnan,Dave W Burt,Jimin George,Matthew T. Biegler,David Iorns,Andrew Digby,Daryl Eason,Taylor Edwards,Mark Wilkinson,George F. Turner,Axel Meyer,Andreas F. Kautt,Paolo Franchini,H. William Detrich,Hannes Svardal,Maximilian Wagner,Gavin J. P. Naylor,Martin Pippel,Milan Malinsky,Mark Mooney,Maria Simbirsky,Brett T. Hannigan,Trevor Pesout,Marlys L. Houck,Ann C Misuraca,Sarah B. Kingan,Richard Hall,Zev N. Kronenberg,Jonas Korlach,Ivan Sović,Christopher Dunn,Zemin Ning,Alex Hastie,Joyce V. Lee,Siddarth Selvaraj,Richard E. Green,Nicholas H. Putnam,Jay Ghurye,Erik Garrison,Ying Sims,Joanna Collins,Sarah Pelan,James Torrance,Alan Tracey,Jonathan Wood,Dengfeng Guan,Sarah E. London,David F. Clayton,Claudio V. Mello,Samantha R. Friedrich,Peter V. Lovell,Ekaterina Osipova,Farooq O. Al-Ajli,Simona Secomandi,Heebal Kim,Constantina Theofanopoulou,Yang Zhou,Robert S. Harris,Kateryna D. Makova,Paul Medvedev,Jinna Hoffman,Patrick Masterson,Karen Clark,Fergal J. Martin,Kevin L. Howe,Paul Flicek,Brian P. Walenz,Woori Kwak,Hiram Clawson,Mark Diekhans,Luis R Nassar,Benedict Paten,Robert H. S. Kraus,Harris A. Lewin,Andrew J. Crawford,M. Thomas P. Gilbert,Guojie Zhang,Byrappa Venkatesh,Robert W. Murphy,Klaus-Peter Koepfli,Beth Shapiro,Warren E. Johnson,Federica Di Palma,Tomas Marques-Bonet,Emma C. Teeling,Tandy Warnow,Jennifer A. Marshall Graves,Oliver A. Ryder,David Haussler,Stephen J. O'Brien,Kerstin Howe,Eugene W. Myers,Richard Durbin,Adam M. Phillippy,Erich D. Jarvis +121 more
TL;DR: The Vertebrate Genomes Project is embarked on, an effort to generate high-quality, complete reference genomes for all ~70,000 extant vertebrate species and help enable a new era of discovery across the life sciences.
Journal ArticleDOI
The axolotl genome and the evolution of key tissue formation regulators
Sergej Nowoshilow,Sergej Nowoshilow,Sergej Nowoshilow,Siegfried Schloissnig,Ji-Feng Fei,Andreas Dahl,Andy Wing Chun Pang,Martin Pippel,Sylke Winkler,Alex Hastie,George R. Young,Juliana G. Roscito,Francisco Falcon,Dunja Knapp,Sean Powell,Alfredo Cruz,Han Cao,Bianca Habermann,Michael Hiller,Elly M. Tanaka,Elly M. Tanaka,Elly M. Tanaka,Eugene W. Myers +22 more
TL;DR: The sequencing and assembly of the 32-gigabase-pair axolotl genome is reported using an approach that combined long-read sequencing, optical mapping and development of a new genome assembler (MARVEL).
Journal ArticleDOI
Six3 overexpression initiates the formation of ectopic retina
TL;DR: Initiation of ectopic retina formation reveals a pivotal role for Six3 in vertebrate retina development and hints at a conserved regulatory network underlying vertebrate and invertebrate eye development.
Journal ArticleDOI
The genome of Schmidtea mediterranea and the evolution of core cellular mechanisms
Markus A. Grohme,Siegfried Schloissnig,Andrei Rozanski,Martin Pippel,George R. Young,Sylke Winkler,Holger Brandl,Ian Henry,Andreas Dahl,Sean Powell,Michael Hiller,Eugene W. Myers,Jochen C. Rink +12 more
TL;DR: The genome assembly of S. mediterranea is reported, using long-read sequencing and a de novo assembler enhanced for low-complexity reads to provide a key model system resource that will be useful for studying regeneration and the evolutionary plasticity of core cell biological mechanisms.