C
Christopher Dunn
Researcher at Pacific Biosciences
Publications - 8
Citations - 3261
Christopher Dunn is an academic researcher from Pacific Biosciences. The author has contributed to research in topics: Genome & Genomics. The author has an hindex of 6, co-authored 7 publications receiving 1785 citations.
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Journal ArticleDOI
Phased diploid genome assembly with single-molecule real-time sequencing
Chen-Shan Chin,Paul Peluso,Fritz J. Sedlazeck,Maria Nattestad,Gregory T. Concepcion,Alicia Clum,Christopher Dunn,Ronan C. O'Malley,Rosa Figueroa-Balderas,Abraham Morales-Cruz,Grant R. Cramer,Massimo Delledonne,Chongyuan Luo,Joseph R. Ecker,Dario Cantu,David R. Rank,Michael C. Schatz,Michael C. Schatz +17 more
TL;DR: The open-source FALCON and FALcon-Unzip algorithms are introduced to assemble long-read sequencing data into highly accurate, contiguous, and correctly phased diploid genomes.
Journal ArticleDOI
Towards complete and error-free genome assemblies of all vertebrate species
Arang Rhie,Shane A. McCarthy,Shane A. McCarthy,Olivier Fedrigo,Joana Damas,Giulio Formenti,Sergey Koren,Marcela Uliano-Silva,William Chow,Arkarachai Fungtammasan,J. H. Kim,Chul Hee Lee,Byung June Ko,Mark Chaisson,Gregory Gedman,Lindsey J. Cantin,Françoise Thibaud-Nissen,Leanne Haggerty,Iliana Bista,Iliana Bista,Michelle Smith,Bettina Haase,Jacquelyn Mountcastle,Sylke Winkler,Sylke Winkler,Sadye Paez,Jason T. Howard,Sonja C. Vernes,Sonja C. Vernes,Sonja C. Vernes,Tanya M. Lama,Frank Grützner,Wesley C. Warren,Christopher N. Balakrishnan,Dave W Burt,Jimin George,Matthew T. Biegler,David Iorns,Andrew Digby,Daryl Eason,Bruce C. Robertson,Taylor Edwards,Mark Wilkinson,George F. Turner,Axel Meyer,Andreas F. Kautt,Andreas F. Kautt,Paolo Franchini,H. William Detrich,Hannes Svardal,Hannes Svardal,Maximilian Wagner,Gavin J. P. Naylor,Martin Pippel,Milan Malinsky,Milan Malinsky,Mark Mooney,Maria Simbirsky,Brett T. Hannigan,Trevor Pesout,Marlys L. Houck,Ann C Misuraca,Sarah B. Kingan,Richard Hall,Zev N. Kronenberg,Ivan Sović,Christopher Dunn,Zemin Ning,Alex Hastie,Joyce V. Lee,Siddarth Selvaraj,Richard E. Green,Nicholas H. Putnam,Ivo Gut,Jay Ghurye,Erik Garrison,Ying Sims,Joanna Collins,Sarah Pelan,James Torrance,Alan Tracey,Jonathan Wood,Robel E. Dagnew,Dengfeng Guan,Dengfeng Guan,Sarah E. London,David F. Clayton,Claudio V. Mello,Samantha R. Friedrich,Peter V. Lovell,Ekaterina Osipova,Farooq O. Al-Ajli,Farooq O. Al-Ajli,Simona Secomandi,Heebal Kim,Constantina Theofanopoulou,Michael Hiller,Yang Zhou,Robert S. Harris,Kateryna D. Makova,Paul Medvedev,Jinna Hoffman,Patrick Masterson,Karen Clark,Fergal J. Martin,Kevin L. Howe,Paul Flicek,Brian P. Walenz,Woori Kwak,Hiram Clawson,Mark Diekhans,Luis R Nassar,Benedict Paten,Robert H. S. Kraus,Robert H. S. Kraus,Andrew J. Crawford,M. Thomas P. Gilbert,M. Thomas P. Gilbert,Guojie Zhang,Byrappa Venkatesh,Robert W. Murphy,Klaus-Peter Koepfli,Beth Shapiro,Beth Shapiro,Warren E. Johnson,Warren E. Johnson,Federica Di Palma,Tomas Marques-Bonet,Emma C. Teeling,Tandy Warnow,Jennifer A. Marshall Graves,Oliver A. Ryder,Oliver A. Ryder,David Haussler,Stephen J. O'Brien,Jonas Korlach,Harris A. Lewin,Kerstin Howe,Eugene W. Myers,Eugene W. Myers,Richard Durbin,Richard Durbin,Adam M. Phillippy,Erich D. Jarvis,Erich D. Jarvis +144 more
TL;DR: The Vertebrate Genomes Project (VGP) as mentioned in this paper is an international effort to generate high quality, complete reference genomes for all of the roughly 70,000 extant vertebrate species and to help to enable a new era of discovery across the life sciences.
Posted ContentDOI
Towards complete and error-free genome assemblies of all vertebrate species
Arang Rhie,Shane A. McCarthy,Olivier Fedrigo,Joana Damas,Giulio Formenti,Sergey Koren,Marcela Uliano-Silva,William Chow,Arkarachai Fungtammasan,Gregory Gedman,Lindsey J. Cantin,Françoise Thibaud-Nissen,Leanne Haggerty,Chul Hee Lee,Byung June Ko,J. H. Kim,Iliana Bista,Michelle Smith,Bettina Haase,Jacquelyn Mountcastle,Sylke Winkler,Sadye Paez,Jason T. Howard,Sonja C. Vernes,Tanya M. Lama,Frank Grützner,Wesley C. Warren,Christopher N. Balakrishnan,Dave W Burt,Jimin George,Matthew T. Biegler,David Iorns,Andrew Digby,Daryl Eason,Taylor Edwards,Mark Wilkinson,George F. Turner,Axel Meyer,Andreas F. Kautt,Paolo Franchini,H. William Detrich,Hannes Svardal,Maximilian Wagner,Gavin J. P. Naylor,Martin Pippel,Milan Malinsky,Mark Mooney,Maria Simbirsky,Brett T. Hannigan,Trevor Pesout,Marlys L. Houck,Ann C Misuraca,Sarah B. Kingan,Richard Hall,Zev N. Kronenberg,Jonas Korlach,Ivan Sović,Christopher Dunn,Zemin Ning,Alex Hastie,Joyce V. Lee,Siddarth Selvaraj,Richard E. Green,Nicholas H. Putnam,Jay Ghurye,Erik Garrison,Ying Sims,Joanna Collins,Sarah Pelan,James Torrance,Alan Tracey,Jonathan Wood,Dengfeng Guan,Sarah E. London,David F. Clayton,Claudio V. Mello,Samantha R. Friedrich,Peter V. Lovell,Ekaterina Osipova,Farooq O. Al-Ajli,Simona Secomandi,Heebal Kim,Constantina Theofanopoulou,Yang Zhou,Robert S. Harris,Kateryna D. Makova,Paul Medvedev,Jinna Hoffman,Patrick Masterson,Karen Clark,Fergal J. Martin,Kevin L. Howe,Paul Flicek,Brian P. Walenz,Woori Kwak,Hiram Clawson,Mark Diekhans,Luis R Nassar,Benedict Paten,Robert H. S. Kraus,Harris A. Lewin,Andrew J. Crawford,M. Thomas P. Gilbert,Guojie Zhang,Byrappa Venkatesh,Robert W. Murphy,Klaus-Peter Koepfli,Beth Shapiro,Warren E. Johnson,Federica Di Palma,Tomas Marques-Bonet,Emma C. Teeling,Tandy Warnow,Jennifer A. Marshall Graves,Oliver A. Ryder,David Haussler,Stephen J. O'Brien,Kerstin Howe,Eugene W. Myers,Richard Durbin,Adam M. Phillippy,Erich D. Jarvis +121 more
TL;DR: The Vertebrate Genomes Project is embarked on, an effort to generate high-quality, complete reference genomes for all ~70,000 extant vertebrate species and help enable a new era of discovery across the life sciences.
Journal ArticleDOI
Long-read sequence assembly of the gorilla genome.
David Gordon,John Huddleston,Mark Chaisson,Christopher M. Hill,Zev N. Kronenberg,Katherine M. Munson,Maika Malig,Archana Raja,Ian T. Fiddes,LaDeana W. Hillier,Christopher Dunn,Carl Baker,Joel Armstrong,Mark Diekhans,Benedict Paten,Jay Shendure,Richard K. Wilson,David Haussler,Chen-Shan Chin,Evan E. Eichler +19 more
TL;DR: The genome assembly that results from using the long-read data provides a more complete picture of gene content, structural variation, and repeat biology, improving population genetic and evolutionary inferences.
Posted ContentDOI
Phased Diploid Genome Assembly with Single Molecule Real-Time Sequencing
Chen-Shan Chin,Paul Peluso,Fritz J. Sedlazeck,Maria Nattestad,Gregory T. Concepcion,Alicia Clum,Christopher Dunn,Ronan C. O'Malley,Rosa Figueroa-Balderas,Abraham Morales-Cruz,Grant R. Cramer,Massimo Delledonne,Chongyuan Luo,Joseph R. Ecker,Dario Cantu,David R. Rank,Michael C. Schatz +16 more
TL;DR: The FALCON-based assemblies were substantially more contiguous and complete than alternate short or long-read approaches, and enabled the study of haplotype structures and heterozygosities between the homologous chromosomes, including identifying widespread heterozygous structural variations within the coding sequences.