Sylvia Boesch

TL;DR: The final analysis of a prospective multicentre study by the European MSA Study Group provides new insights into the evolution of MSA based on a follow-up period that exceeds that of previous studies.

TL;DR: Results show that DWI detects basal ganglia abnormalities in PSP patients within few years of disease onset, discriminating patients with PSP from those with PD, but not fromThose with MSA-P.

TL;DR: This Review provides guidelines, from a European perspective, for the diagnosis of Friedreich ataxia, differential diagnosis of ataxias and genetic counseling, and treatment of neurological and non-neurological symptoms.

TL;DR: This study provides quantitative data on the progression of the most common spinocerebellar ataxias based on a follow-up period that exceeds those of previous studies and could prove useful for sample size calculation and patient stratification in interventional trials.

TL;DR: A combination of two out of six red flag categories as additional diagnostic criteria for probable MSA‐P is proposed and 76.5% of them would have been correctly diagnosed as probable Msa‐P 15.9 months earlier than with the Consensus criteria alone.