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Pavithra Rajagopalan
Researcher at University of Pennsylvania
Publications - 31
Citations - 2389
Pavithra Rajagopalan is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Cancer & Head and neck squamous-cell carcinoma. The author has an hindex of 10, co-authored 25 publications receiving 2012 citations. Previous affiliations of Pavithra Rajagopalan include KIIT University.
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Journal ArticleDOI
A draft map of the human proteome
Min-Sik Kim,Sneha M. Pinto,Derese Getnet,Raja Sekhar Nirujogi,Srikanth S. Manda,Raghothama Chaerkady,Anil K. Madugundu,Dhanashree S. Kelkar,Ruth Isserlin,Shobhit Jain,Joji Kurian Thomas,Babylakshmi Muthusamy,Pamela Leal-Rojas,Pamela Leal-Rojas,Praveen Kumar,Nandini A. Sahasrabuddhe,Lavanya Balakrishnan,Jayshree Advani,Bijesh George,Santosh Renuse,Lakshmi Dhevi N. Selvan,Arun H. Patil,Vishalakshi Nanjappa,Aneesha Radhakrishnan,Samarjeet Prasad,Tejaswini Subbannayya,Rajesh Raju,Manish Kumar,Sreelakshmi K. Sreenivasamurthy,Arivusudar Marimuthu,Gajanan Sathe,Sandip Chavan,Keshava K. Datta,Yashwanth Subbannayya,Apeksha Sahu,Soujanya D. Yelamanchi,Savita Jayaram,Pavithra Rajagopalan,Jyoti Sharma,Krishna R Murthy,Nazia Syed,Renu Goel,Aafaque Ahmad Khan,Sartaj Ahmad,Gourav Dey,Keshav Mudgal,Aditi Chatterjee,Tai-Chung Huang,Jun Zhong,Xinyan Wu,Patrick G. Shaw,Donald Freed,Muhammad Saddiq Zahari,Kanchan K Mukherjee,Subramanian Shankar,Anita Mahadevan,Henry H N Lam,Chris J. Mitchell,Susarla K. Shankar,Parthasarathy Satishchandra,John T. Schroeder,Ravi Sirdeshmukh,Anirban Maitra,Steven D. Leach,Charles G. Drake,Marc K. Halushka,T. S. Keshava Prasad,Ralph H. Hruban,Candace L. Kerr,Candace L. Kerr,Gary D. Bader,Christine A. Iacobuzio-Donahue,Harsha Gowda,Akhilesh Pandey +73 more
TL;DR: A draft map of the human proteome is presented using high-resolution Fourier-transform mass spectrometry to discover a number of novel protein-coding regions, which includes translated pseudogenes, non-c coding RNAs and upstream open reading frames.
Journal ArticleDOI
Integrating transcriptomic and proteomic data for accurate assembly and annotation of genomes
T. S. Keshava Prasad,T. S. Keshava Prasad,Ajeet Kumar Mohanty,Ajeet Kumar Mohanty,Manish Kumar,Sreelakshmi K. Sreenivasamurthy,Gourav Dey,Raja Sekhar Nirujogi,Sneha M. Pinto,Anil K. Madugundu,Arun H. Patil,Jayshree Advani,Srikanth S. Manda,Manoj Kumar Gupta,Sutopa B. Dwivedi,Dhanashree S. Kelkar,Brantley Hall,Xiaofang Jiang,Ashley Peery,Pavithra Rajagopalan,Soujanya D. Yelamanchi,Hitendra S. Solanki,Remya Raja,Gajanan Sathe,Sandip Chavan,Renu Verma,Krishna Patel,Ankit P. Jain,Nazia Syed,Keshava K. Datta,Aafaque Ahmed Khan,Manjunath Dammalli,Savita Jayaram,Aneesha Radhakrishnan,Chris J. Mitchell,Chan Hyun Na,Nirbhay Kumar,Photini Sinnis,Igor V. Sharakhov,Charles Wang,Harsha Gowda,Zhijian Tu,Ashwani Kumar,Akhilesh Pandey +43 more
TL;DR: The data provide a framework for how future genome sequencing efforts should incorporate transcriptomic and proteomic analysis in combination with simultaneous manual curation to achieve near complete assembly and accurate annotation of genomes.
Journal ArticleDOI
Proteomics of human aqueous humor.
Krishna R Murthy,Pavithra Rajagopalan,Sneha M. Pinto,Jayshree Advani,Praveen R Murthy,Renu Goel,Yashwanth Subbannayya,Lavanya Balakrishnan,Mahashweta Dash,Abhijith K. Anil,Srikanth S. Manda,Raja Sekhar Nirujogi,Dhanashree S. Kelkar,Gajanan Sathe,Gourav Dey,Aditi Chatterjee,Harsha Gowda,Shukti Chakravarti,Subramanian Shankar,Nandini A. Sahasrabuddhe,Bipin G. Nair,B. L. Somani,T. S. Keshava Prasad,Akhilesh Pandey +23 more
TL;DR: This study comprehensively reports 386 novel proteins that have important potential as biomarker candidates for future research into personalized medicine and diagnostics aimed towards improving visual health.
Journal ArticleDOI
LC-MS-based serum metabolomic analysis reveals dysregulation of phosphatidylcholines in esophageal squamous cell carcinoma.
Sartaj Ahmad Mir,Pavithra Rajagopalan,Ankit P. Jain,Aafaque Ahmad Khan,Keshava K. Datta,Sonali V. Mohan,Syed Lateef,Nandini A. Sahasrabuddhe,B. L. Somani,T. S. Keshava Prasad,Aditi Chatterjee,K.V. Veerendra Kumar,M. Vijayakumar,Rekha V. Kumar,Seetaramanjaneyulu Gundimeda,Akhilesh Pandey,Harsha Gowda +16 more
TL;DR: Phosphatidylcholine metabolism was found to be significantly altered in ESCC, and the use of mass spectrometry-based metabolomic analysis to characterize molecular alterations associated with ESCC is illustrated.
Journal ArticleDOI
Identifying predictors of HPV-related head and neck squamous cell carcinoma progression and survival through patient-derived models.
Nicole D. Facompre,Pavithra Rajagopalan,Varun Sahu,Alexander T. Pearson,Kathleen T. Montone,Claire D. James,Frederico O. Gleber-Netto,Gregory S. Weinstein,Jalal B. Jalaly,Alexander Lin,Anil K. Rustgi,Hiroshi Nakagawa,Joseph A. Califano,Curtis R. Pickering,Elizabeth A. White,Bradford E. Windle,Iain M. Morgan,Roger B. Cohen,Phyllis A. Gimotty,Devraj Basu,Devraj Basu +20 more
TL;DR: This study establishes the first well‐characterized panel of patient‐derived xenografts and organoids from HPV+ HNSCCs while determining fidelity of the models to the distinguishing genetic features of this cancer type and reveals novel potential applications of quantifying mutational burden and viral oncogene functions for biomarker development.