M
Masanori Kasahara
Researcher at Hokkaido University
Publications - 209
Citations - 10850
Masanori Kasahara is an academic researcher from Hokkaido University. The author has contributed to research in topics: Major histocompatibility complex & Gene. The author has an hindex of 55, co-authored 208 publications receiving 10122 citations. Previous affiliations of Masanori Kasahara include University of Miami & Graduate University for Advanced Studies.
Papers
More filters
Journal ArticleDOI
Origin and evolution of the adaptive immune system: genetic events and selective pressures
TL;DR: Insight is offered into the latest advances in this field of adaptive immune system research and speculate on the selective pressures that led to the emergence and maintenance of the AIS.
Journal ArticleDOI
Elephant shark genome provides unique insights into gnathostome evolution
Byrappa Venkatesh,Byrappa Venkatesh,Alison P. Lee,Vydianathan Ravi,Ashish K. Maurya,Michelle M. Lian,Jeremy B. Swann,Yuko Ohta,Martin F. Flajnik,Yoichi Sutoh,Masanori Kasahara,Shawn Hoon,Vamshidhar Gangu,Scott William Roy,Manuel Irimia,Vladimir Korzh,Igor Kondrychyn,Zhi Wei Lim,Boon Hui Tay,Sumanty Tohari,Kiat Whye Kong,Shufen Ho,Belen Lorente-Galdos,Belen Lorente-Galdos,Javier Quilez,Javier Quilez,Tomas Marques-Bonet,Tomas Marques-Bonet,Brian J. Raney,Philip W. Ingham,Alice Tay,LaDeana W. Hillier,Patrick Minx,Thomas Boehm,Richard K. Wilson,Sydney Brenner,Wesley C. Warren +36 more
TL;DR: The whole-genome analysis of a cartilaginous fish, the elephant shark (Callorhinchus milii), finds that the C. milii genome is the slowest evolving of all known vertebrates, and features extensive synteny conservation with tetrapod genomes, making it a good model for comparative analyses of gnathostome genomes.
Journal ArticleDOI
The amphioxus genome illuminates vertebrate origins and cephalochordate biology
Linda Z. Holland,Ricard Albalat,Kaoru Azumi,Èlia Benito-Gutiérrez,Matthew J. Blow,Marianne Bronner-Fraser,Frédéric Brunet,Thomas Butts,Simona Candiani,Larry J. Dishaw,Larry J. Dishaw,David E. K. Ferrier,David E. K. Ferrier,Jordi Garcia-Fernàndez,Jeremy J. Gibson-Brown,Carmela Gissi,Adam Godzik,Finn Hallböök,Dan Hirose,Kazuyoshi Hosomichi,Tetsuro Ikuta,Hidetoshi Inoko,Masanori Kasahara,Jun Kasamatsu,Takeshi Kawashima,Takeshi Kawashima,Ayuko Kimura,Masaaki Kobayashi,Zbynek Kozmik,Kaoru Kubokawa,Vincent Laudet,Gary W. Litman,Gary W. Litman,Alice C. McHardy,Alice C. McHardy,Daniel Meulemans,Masaru Nonaka,Robert Piotr Olinski,Zeev Pancer,Len A. Pennacchio,Mario Pestarino,Jonathan P. Rast,Isidore Rigoutsos,Marc Robinson-Rechavi,Graeme J. Roch,Hidetoshi Saiga,Yasunori Sasakura,Masanobu Satake,Yutaka Satou,Michael Schubert,Nancy M. Sherwood,Takashi Shiina,Naohito Takatori,Naohito Takatori,Javier Tello,Pavel Vopalensky,Shuichi Wada,Anlong Xu,Yuzhen Ye,Keita Yoshida,Fumiko Yoshizaki,Jr-Kai Yu,Qing Zhang,Christian M. Zmasek,Pieter J. de Jong,Kazutoyo Osoegawa,Nicholas H. Putnam,Daniel S. Rokhsar,Daniel S. Rokhsar,Noriyuki Satoh,Noriyuki Satoh,Peter W. H. Holland +71 more
TL;DR: The results indicate that the amphioxus genome is elemental to an understanding of the biology and evolution of nonchordate deuterostomes, invertebrate chordates, and vertebrates.
Journal ArticleDOI
Comparative genomics of the MHC: glimpses into the evolution of the adaptive immune system.
TL;DR: Three paralogous regions of the human genome contain sets of linked genes homologous to various loci in the MHC class I, class II, and/or class III regions, providing insight into the organization of the "proto MHC" before the emergence of the adaptive immune system in the jawed vertebrates.
Journal ArticleDOI
The MHC class I ligand-generating system: roles of immunoproteasomes and the interferon-4gMY-inducible proteasome activator PA28
TL;DR: Production of antigenic peptides that serve as MHC class I ligands is essential for initiation of cell‐mediated immunity, suggesting that modifications and renewal of pre‐existing non‐immune genes were instrumental in the emergence of adaptive immunity.