T
Thomas Eisenreich
Researcher at Rockefeller University
Publications - 15
Citations - 4384
Thomas Eisenreich is an academic researcher from Rockefeller University. The author has contributed to research in topics: Chromosomal translocation & Cytidine deaminase. The author has an hindex of 15, co-authored 15 publications receiving 4109 citations. Previous affiliations of Thomas Eisenreich include Howard Hughes Medical Institute.
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Journal ArticleDOI
Visualizing dendritic cell networks in vivo.
Randall L Lindquist,Guy Shakhar,Diana Dudziak,Hedda Wardemann,Thomas Eisenreich,Thomas Eisenreich,Michael L. Dustin,Michel C. Nussenzweig,Michel C. Nussenzweig +8 more
TL;DR: Two-photon microscopy of lymph nodes in live mice showed that most of the steady-state DCs were enmeshed in an extensive network and remained in place while actively probing adjacent T cells with their processes.
Journal ArticleDOI
HIV therapy by a combination of broadly neutralizing antibodies in humanized mice
Florian Klein,Ariel Halper-Stromberg,Joshua A. Horwitz,Henning Gruell,Henning Gruell,Johannes F. Scheid,Johannes F. Scheid,Stylianos Bournazos,Hugo Mouquet,Linda Spatz,Linda Spatz,Ron Diskin,Alexander Abadir,Trinity Zang,Marcus Dorner,Eva Billerbeck,Rachael N. Labitt,Christian Gaebler,Christian Gaebler,Paola Marcovecchio,Reha Baris Incesu,Thomas Eisenreich,Paul D. Bieniasz,Paul D. Bieniasz,Michael S. Seaman,Pamela J. Bjorkman,Jeffrey V. Ravetch,Alexander Ploss,Michel C. Nussenzweig,Michel C. Nussenzweig +29 more
TL;DR: Combinations of potent monoclonal antibodies can effectively control HIV-1 replication in humanized mice, and should be re-examined as a therapeutic modality in HIV- 1-infected individuals.
Journal ArticleDOI
MicroRNA-155 Suppresses Activation-Induced Cytidine Deaminase-Mediated Myc-Igh Translocation
Yair Dorsett,Kevin M. McBride,Mila Jankovic,Anna Gazumyan,Anna Gazumyan,To-Ha Thai,Davide F. Robbiani,Michela Di Virgilio,Bernardo Reina San-Martin,Gordon F. Heidkamp,Tanja A. Schwickert,Thomas Eisenreich,Klaus Rajewsky,Michel C. Nussenzweig,Michel C. Nussenzweig +14 more
TL;DR: It is indicated that miR-155 can act as a tumor suppressor by reducing potentially oncogenic translocations generated by AID.
Journal ArticleDOI
AID Is Required for c-myc/IgH Chromosome Translocations In Vivo
Almudena R. Ramiro,Mila Jankovic,Thomas Eisenreich,Thomas Eisenreich,Simone Difilippantonio,Selina Chen-Kiang,Masamichi Muramatsu,Tasuku Honjo,André Nussenzweig,Michel C. Nussenzweig,Michel C. Nussenzweig +10 more
TL;DR: It is reported that AID is essential for the c-myc/IgH chromosome translocations induced by IL6, which are associated with Burkitt's lymphoma in humans and with pristane- and IL6-induced plasmacytomas in mice.
Journal ArticleDOI
Feedback control of regulatory T cell homeostasis by dendritic cells in vivo
Guillaume Darrasse-Jèze,Stephanie Deroubaix,Hugo Mouquet,Gabriel D. Victora,Thomas Eisenreich,Kai-Hui Yao,Revati F. Masilamani,Michael L. Dustin,Alexander Y. Rudensky,Alexander Y. Rudensky,Kang Liu,Michel C. Nussenzweig,Michel C. Nussenzweig +12 more
TL;DR: The increase in T reg cells induced by DC expansion is sufficient to prevent type 1 autoimmune diabetes and IBD, which suggests that interference with this feedback loop will create new opportunities for immune-based therapies.