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Fumihiko Takeshita

Researcher at Yokohama City University

Publications -  71
Citations -  13861

Fumihiko Takeshita is an academic researcher from Yokohama City University. The author has contributed to research in topics: Innate immune system & Immune system. The author has an hindex of 40, co-authored 71 publications receiving 12584 citations. Previous affiliations of Fumihiko Takeshita include Daiichi Sankyo & Center for Biologics Evaluation and Research.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Daniel J. Klionsky, +235 more
- 16 Feb 2008 - 
TL;DR: A set of guidelines for the selection and interpretation of the methods that can be used by investigators who are attempting to examine macroautophagy and related processes, as well as by reviewers who need to provide realistic and reasonable critiques of papers that investigate these processes are presented.
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A Toll-like receptor–independent antiviral response induced by double-stranded B-form DNA

Ken Ishii, +15 more
- 01 Jan 2006 - 
TL;DR: It is shown that intracellular administration of double-stranded B-form DNA triggered antiviral responses including production of type I interferons and chemokines independently of Toll-like receptors or the helicase RIG-I.
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TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines

Ken Ishii, +10 more
- 07 Feb 2008 - 
TL;DR: It is demonstrated in vivo that TANK-binding kinase 1 (TBK1), a non-canonical IκB kinase, mediates the adjuvant effect of DNA vaccines and is essential for its immunogenicity in mice.
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Cutting Edge: Role of Toll-Like Receptor 9 in CpG DNA-Induced Activation of Human Cells

Fumihiko Takeshita, +6 more
- 01 Oct 2001 - 
TL;DR: Findings indicate that hTLR9 plays a critical role in the CpG DNA-mediated activation of human cells and evolutionary divergence between TLR9 molecules underlies species-specific differences in the recognition of bacterial DNA.