W
W. Peter Vandertop
Researcher at University of Amsterdam
Publications - 192
Citations - 8800
W. Peter Vandertop is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Subarachnoid hemorrhage & Glioma. The author has an hindex of 44, co-authored 165 publications receiving 7355 citations. Previous affiliations of W. Peter Vandertop include VU University Medical Center & VU University Amsterdam.
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Journal ArticleDOI
Cognitive and radiological effects of radiotherapy in patients with low-grade glioma: long-term follow-up
Linda Douw,Martin Klein,Selene S. A. A. Fagel,Josje van den Heuvel,Martin J.B. Taphoorn,Martin J.B. Taphoorn,Neil K. Aaronson,Tjeerd J. Postma,W. Peter Vandertop,Jacob J. Mooij,Rudolf H. Boerman,Guus Beute,Jasper D. Sluimer,Ben J. Slotman,Jaap C. Reijneveld,Jan J. Heimans +15 more
TL;DR: In this paper, the authors assessed the radiological and cognitive abnormalities in survivors of low-grade glioma (LGG) at a mean of 12 years after first diagnosis.
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Treatment of Brain Arteriovenous Malformations A Systematic Review and Meta-analysis
Janneke van Beijnum,H. Bart van der Worp,Dennis R. Buis,Rustam Al-Shahi Salman,L. Jaap Kappelle,Gabriel J.E. Rinkel,Jan Willem Berkelbach van der Sprenkel,W. Peter Vandertop,Ale Algra,Catharina J.M. Klijn +9 more
TL;DR: Although case fatality after treatment has decreased over time, treatment of brain AVM remains associated with considerable risks and incomplete efficacy, and Randomized controlled trials comparing different treatment modalities appear justified.
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IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors.
Fonnet E. Bleeker,Simona Lamba,Sieger Leenstra,Dirk Troost,Theo J. M. Hulsebos,W. Peter Vandertop,W. Peter Vandertop,Milo Frattini,Francesca Molinari,Margaret A. Knowles,Aniello Cerrato,Monica Rodolfo,Aldo Scarpa,Lara Felicioni,Fiamma Buttitta,Sara Malatesta,Antonio Marchetti,Alberto Bardelli +17 more
TL;DR: In this paper, the authors search for mutations at position R132 of the IDH1 gene in a panel of 672 tumor samples, including high-grade glioma, gastrointestinal stromal tumors (GIST), melanoma, bladder, breast, colorectal, lung, ovarian, pancreas, prostate, and thyroid carcinoma specimens.
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Epilepsy in low-grade gliomas: the impact on cognitive function and quality of life.
Martin Klein,Nadine H. J. Engelberts,Henk M. van der Ploeg,Dorothée G.A. Kasteleijn-Nolst Trenité,Neil K. Aaronson,Martin J.B. Taphoorn,Hans Baaijen,W. Peter Vandertop,Martin J. Muller,Tjeerd J. Postma,Jan J. Heimans +10 more
TL;DR: Low‐grade glioma patients suffer from a number of neuropsychological and psychological problems that are aggravated by the severity of epilepsy and by the intensity of the treatment.
Journal ArticleDOI
Blood platelets contain tumor-derived RNA biomarkers
R. Jonas A. Nilsson,R. Jonas A. Nilsson,Leonora Balaj,Leonora Balaj,Esther Hulleman,Sjoerd van Rijn,D. Michiel Pegtel,Maudy Walraven,Anders Widmark,Winald R. Gerritsen,Henk M.W. Verheul,W. Peter Vandertop,David P. Noske,Johan Skog,Thomas Wurdinger,Thomas Wurdinger +15 more
TL;DR: It is demonstrated that tumor cells transfer (mutant) RNA into blood platelets in vitro and in vivo, and it is shown that platelets isolated from glioma and prostate cancer patients contain the cancer-associated RNA biomarkers EGFRvIII and PCA3, respectively.