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William W. Busse
Researcher at University of Wisconsin-Madison
Publications - 740
Citations - 62685
William W. Busse is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Asthma & Eosinophil. The author has an hindex of 115, co-authored 697 publications receiving 56703 citations. Previous affiliations of William W. Busse include National Institutes of Health & University at Buffalo.
Papers
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Journal ArticleDOI
Rhinovirus upper respiratory infection increases airway hyperreactivity and late asthmatic reactions.
TL;DR: It is found that not only does a RV respiratory tract illness enhance airway reactivity, but it also predisposes the allergic patient to develop LARs, which may be an important factor in virus-induced bronchial hyperresponsiveness.
Journal ArticleDOI
Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia
Michel Laviolette,David Gossage,Gail M. Gauvreau,Richard Leigh,Ron Olivenstein,Rohit K. Katial,William W. Busse,Sally E. Wenzel,Yanping Wu,Vivekananda Datta,Roland Kolbeck,Nestor A. Molfino +11 more
TL;DR: Single-dose intravenous and multiple-dose subcutaneous benralizumab reduced eosinophil counts in airway mucosa/submucosa and sputum and suppressed eosInophils counts in bone marrow and peripheral blood and the safety profile supports further development.
Journal ArticleDOI
Severe exacerbations and decline in lung function in asthma.
TL;DR: Severe asthma exacerbations are associated with a more rapid decline in lung function and treatment with low doses of inhaled corticosteroid is associated with an attenuation of the decline.
Book
Asthma and Rhinitis
TL;DR: Part 1: Disease Classification Part 2: Epidemiology Part 3: Normal Anatomy, Development and Physiology Part 4: Pathology Part 5: Mast Cells And Basophils Part 6: Eosinophils
Journal Article
Omalizumab in Severe Allergic Asthma Inadequately Controlled With Standard Therapy
Nicola A. Hanania,Oral Alpan,Daniel L. Hamilos,John J. Condemi,Irmarie Reyes-Rivera,Jin Zhu,Karin Rosén,Mark D. Eisner,Dennis A. Wong,William W. Busse +9 more
TL;DR: In this paper, a randomized trial evaluated the efficacy of inhaled corticosteroids (ICS) and long-acting β2-agonists (LABAs) for severe asthma in some patients.