W
William W. Busse
Researcher at University of Wisconsin-Madison
Publications - 740
Citations - 62685
William W. Busse is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Asthma & Eosinophil. The author has an hindex of 115, co-authored 697 publications receiving 56703 citations. Previous affiliations of William W. Busse include National Institutes of Health & University at Buffalo.
Papers
More filters
Journal ArticleDOI
Allergic asthma and an anti-CD23 mAb (IDEC-152): results of a phase I, single-dose, dose-escalating clinical trial
TL;DR: In this article, the authors investigated the safety, clinical activity, and pharmacokinetic profile of IDEC-152, an IgG1 anti-CD23 antibody, in patients with mild-to-moderate persistent allergic asthma.
Journal ArticleDOI
The Appearance of Hypodense Eosinophils in Antigen-dependent Late Phase Asthma
TL;DR: The data suggest that in vivo activation of asthma by inhaled antigen increases the proportion of peripheral blood EOS that are hypodense but only in those patients with both an IAR and late phase asthma reaction (LAR).
Journal ArticleDOI
Where is the allergic reaction in ragweed asthma?: II. Demonstration of ragweed antigen in airborne particles smaller than pollen
TL;DR: Airborne particles, less than 5μ in diameter, capable of neutralizing ragweed reagin are demonstrated, which could penetrate to lower airways and initiate an allergic reaction there.
Journal ArticleDOI
Asthma phenotypes in inner-city children.
Edward M. Zoratti,Rebecca Z. Krouse,Denise C. Babineau,Jacqueline A. Pongracic,George T. O'Connor,Robert A. Wood,Gurjit K. Khurana Hershey,Carolyn M. Kercsmar,Rebecca S. Gruchalla,Meyer Kattan,Stephen J. Teach,Steven M. Sigelman,Peter J. Gergen,Alkis Togias,Cynthia M. Visness,William W. Busse,Andrew H. Liu,Andrew H. Liu +17 more
TL;DR: Allergy distinguishes asthma phenotypes in urban children and a symptomatic phenotype with little allergy or allergic inflammation was identified among inner-city children receiving guidelines-based management.
Journal ArticleDOI
Mechanisms of persistent airway inflammation in asthma. A role for T cells and T-cell products.
TL;DR: The data presented indicate how the T cell may be a pivotal cell to direct features of allergic inflammation in asthma, how it may be able to transfer hyperresponsiveness, which is a feature of bronchial asthma, and how an important precipitant of asthma, viral respiratory infections, may participate in this process.