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William W. Busse
Researcher at University of Wisconsin-Madison
Publications - 740
Citations - 62685
William W. Busse is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Asthma & Eosinophil. The author has an hindex of 115, co-authored 697 publications receiving 56703 citations. Previous affiliations of William W. Busse include National Institutes of Health & University at Buffalo.
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Reduced granulocyte response to isoproterenol, histamine, and prostaglandin E1 after in vitro incubation with Rhinovirus 16.
TL;DR: After an in vitro incubation of polymorphonuclear leukocytes with rhinovirus 16, the granulocyte response to ISO, HIS, and PGE1 was significantly reduced, and this change in agonist response was proportional to the virus dosage, maximal at 37 degrees C and after a 60-min incubation period.
Journal ArticleDOI
Phenotype of asthmatics with increased airway S -nitrosoglutathione reductase activity
Nadzeya Marozkina,Xin-Qun Wang,Vitali I. Stsiapura,Anne M. Fitzpatrick,Silvia Carraro,Gregory A. Hawkins,Eugene R. Bleecker,Deborah A. Meyers,Nizar N. Jarjour,Sean B. Fain,Sally E. Wenzel,William W. Busse,Mario Castro,Reynold A. Panettieri,Wendy C. Moore,Stephen J. Lewis,Lisa A. Palmer,Talissa A. Altes,Eduard E. de Lange,Serpil C. Erzurum,W. Gerald Teague,Benjamin Gaston +21 more
TL;DR: An early-onset, allergic phenotype characterises the asthma population with increased S-nitrosoglutathione reductase activity, which was higher in airway epithelium than in smooth muscle and was increased in regions of the asthmatic lung with decreased airflow.
Journal ArticleDOI
Asthma morbidity among inner-city adolescents receiving guidelines-based therapy: Role of predictors in the setting of high adherence
Rebecca S. Gruchalla,Hugh A. Sampson,Elizabeth C. Matsui,Gloria David,Peter J. Gergen,Agustin Calatroni,Mark A. Brown,Andrew H. Liu,Gordon R. Bloomberg,James F. Chmiel,Rajesh Kumar,Carin I. Lamm,Ernestine Smartt,Christine A. Sorkness,Suzanne Steinbach,Kelly D. Stone,Stanley J. Szefler,William W. Busse +17 more
TL;DR: The usual predictors of future disease activity have little predictive power when applied to a highly adherent population with persistent asthma that is receiving guidelines-based care, and new predictors need to be identified that are able to measure the continued fluctuation of disease that persists in highly adherent, well-treated populations such as the one studied.
Journal ArticleDOI
Failure of catecholamines to inhibit epidermal mitosis in vitro.
TL;DR: It was concluded that inhibition of DNA synthesis is a beta adrenergic effect, and the cells of patients with atopic eczema are insensitive to beta stimulation.
Journal ArticleDOI
Expression quantitative trait locus fine mapping of the 17q12-21 asthma locus in African American children: a genetic association and gene expression study
Carole Ober,Chris McKennan,Kevin M. Magnaye,Matthew C. Altman,Charles Washington,Catherine Stanhope,Katherine A. Naughton,Mario G. Rosasco,Leonard B. Bacharier,Dean Billheimer,Diane R. Gold,Diane R. Gold,Lisa Gress,Tina Hartert,Suzanne Havstad,Gurjit K. Khurana Hershey,Brian Hallmark,D. Kyle Hogarth,Daniel J. Jackson,Christine Cole Johnson,Meyer Kattan,Robert F. Lemanske,S.V. Lynch,Eneida A. Mendonca,Eneida A. Mendonca,Eneida A. Mendonca,Rachel L. Miller,Edward T. Naureckas,George T. O'Connor,Christine M. Seroogy,Ganesa Wegienka,Steven R. White,Robert A. Wood,Anne L. Wright,Edward M. Zoratti,Fernando D. Martinez,Dennis R. Ownby,Dan L. Nicolae,Albert M. Levin,James E. Gern,Niek B. Achten,John Ainsworth,Nonna Akkerman,Elizabeth L. Anderson,Larry J. Anderson,Howard Andrews,Elizabeth Armagost,Mary Ann Aubuchon,Julia Bach,Leonard B. Bacharier,Kathrine L. Barnes,Charles Barone,Irma Bauer,Paloma I. Beamer,Patrice Becker,Alyssa Bednarek,Stacey Bellemore,Casper G. Bendixsen,Jocelyn M. Biagini Myers,Christine Billstrand,Geraldine Birg,Shirley Blocki,Gordon R. Bloomberg,Kevin R. Bobbitt,Yury A. Bochkov,Karen Bourgeois,Homer A. Boushey,Rebecca A. Brockman-Schneider,Steven M. Brunwasser,Richard Budrevich,Jeffrey W. Burkle,William W. Busse,Agustin Calatroni,Janice Campbell,Kirsten T. Carlson-Dakes,Andrea E. Cassidy-Bushrow,James D. Chappell,Deborah Chasman,Teresa M. Chipps,Tatiana Chirkova,Deanna Cole,Alexandra Connolly,Michelle Cootauco,Kaitlin Costello,Philip Couch,Brent A. Coull,Mark Craven,Gina Crisafi,William W. Cruikshank,Kristi Curtsinger,Adnan Custovic,Suman R. Das,Douglas F. DaSilva,Soma Datta,Brent Davidson,Lydia de la Ossa,Mark K. Devries,Qian Di,Samara Dixon,Erin Donnerbauer,Marian Dorst,Susan Doyle,Amy Dresen,William D. Dupont,Janet Durrange,Heidi Erickson,Michael D. Evans,Jerel M. Ezell,Leanna Farnham,Roxanne Filardo-Collins,Salvatore Finazzo,Zachary Flege,Conner Fleurat,Heather Floerke,Dorothy Floerke,Terry Foss,Angela Freie,Wayne Frome,Samantha R. Fye,Lisa Gagalis,Rebecca Gammell,Ronald E. Gangnon,James E. Ge,Tebeb Gebretsadik,Peter J. Gergen,Heike Gibson,Edlira Gjerasi,Nicole Gonzalez,Kayla Goodman,Kristine Grindle,Taylor Groeschen,Marilyn Halonen,Jaime Hart,Tina V. Hartert,Patrick Heinritz,Sharon Hensley Alford,Julie B. Herbstman,Kellie Hernandez,Lori Hoepner,Samadhan J. Jadhao,Katy F. Jaffee,Peter James,Jacqueline Jezioro,Marcia Jimenez Pescador,Tara Johnson,Camille Johnson,Amelia Jones,Kyra Jones,Paul W. Jones,Carolina Jordan,Christine L.M. Joseph,Kristina Keidel,Matthew C. Keifer,Rick Kelley,Gurgit K. Khurana Hershey,Haejin Kim,Itai Kloog,Tammy Kronenwetter Koepel,Clint Koerkenmeier,Laura Ladick,Carin Lamm,Emma K. Larkin,Howard M. Lederman,Aviva Lee-Parritz,Stephanie Leimenstoll,Grace K. LeMasters,Jessica Levine,Xinhua Liu,Z. Liu,Silvia Lopez,Nathan Lothrop,Stephanie Lovinsky-Desir,Nicholas W. Lukacs,Susan V. Lynch,Christian E. Lynch,Erik Mann,Jennifer Martin,Lisa J. Martin,Elizabeth C. Matsui,Katherine McCauley,Megan D McCollum,Judith McCullough,Chris G. McKennon,Jennifer K. Meece,Eneida A. Mendonça,Lance D. Mikus,Patricia A. Minton,Herman Mitchell,Vicki Moon,Paul E. Moore,Wayne J. Morgan,Valerie Morgan,David Morgan,Liza Murrison,Charlotte Nicholas,Daniel Nicolae,Adam Nunez,George T. O'Connor,Sharon O'Toole,Brent F. Olson,Irene M. Ong,Sarah Osmundson,Tressa Pappas,Frederica P. Perera,Matthew S. Perzanowski,Edward Peterson,Marcela Pierce,Penny Price-Johnson,Victoria Rajamanickam,Judyth Ramirez,Kimberly L. Ray,Megan Renneberg,Weeberb J. Requia,Kylie Riley,Janelle Rivera,Neisha Rivers,Kathy A. Roberg,Theresa Rogers,Christian Rosas-Salazar,Pat Russell,Patrick H. Ryan,Yoel Sadovsky,L.E.P. Salazar,Hugh A. Sampson,Megan Sandel,Nathan Schoettler,Joel Schwartz,Dena Scott,Renee Sharp,Meghan H. Shilts,Steve Sigelman,Anne Marie Singh,Alexandra R. Sitarik,Ernestine Smartt,Ronald L. Sorkness,Christine A. Sorkness,Amber Spangenberg,Rhoda Sperling,David Spies,Debra A. Stern,Brandy Stoffel,R. Stokes Peebles,Gina Stouffer,Cathey Strauchman Boyer,Caitlin Suddeuth,Umberto Tachinardi,Deliang Tang,Zhengzheng Tang,Jena Tate,William Taylor,Krista Tensing,Elizabeth Tesson,Kathy Thompson,Emma E. Thompson,Christopher J. Tisler,Alkis Togias,Kedir N. Turi,Victoria Turner,Marina Tuzova,Jeffrey J. VanWormer,Cynthia M. Visness,Rose F. Vrtis,Anthony Wahlman,Lena Wang,Karen Wells,William Wentworth-Sheilds,Lisa M. Wheatley,Nitsa Whitney,L. Keoki Williams,Frank Witter,Christopher R. Wolfe,Kimberley J. Woodcroft,Kim B. Woodward,Rosalind J. Wright,Pingsheng Wu,Melissa Yaeger,Perri Yaniv,Antonella Zanobetti,Shirley L. Zhang,Patricia Zook +279 more
TL;DR: This study suggests that SNPs regulating GSDMB expression in airway epithelial cells have a major role in childhood-onset asthma, whereasSNPs regulating the expression levels of 17q12-21 genes in resting blood cells are not central asthma risk.