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William W. Busse
Researcher at University of Wisconsin-Madison
Publications - 740
Citations - 62685
William W. Busse is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Asthma & Eosinophil. The author has an hindex of 115, co-authored 697 publications receiving 56703 citations. Previous affiliations of William W. Busse include National Institutes of Health & University at Buffalo.
Papers
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Journal ArticleDOI
Combined Analysis of Asthma Safety Trials of Long-Acting β2-Agonists
William W. Busse,Eric D. Bateman,Arthur L. Caplan,H. William Kelly,Paul M. O'Byrne,Klaus F. Rabe,Vernon M. Chinchilli +6 more
TL;DR: Combination therapy with a LABA plus an inhaled glucocorticoid did not result in a significantly higher risk of serious asthma‐related events than treatment with an inhaler alone but resulted in significantly fewer asthma exacerbations.
Journal ArticleDOI
Once-daily fluticasone furoate (FF)/vilanterol reduces risk of severe exacerbations in asthma versus FF alone
Eric D. Bateman,Paul M. O'Byrne,William W. Busse,Jan Lötvall,Eugene R. Bleecker,Leslie Andersen,Loretta Jacques,Lucy Frith,Jessica Lim,Ashley Woodcock +9 more
TL;DR: Once-daily FF/VI reduced the risk of severe asthma exacerbations and improved lung function compared with FF alone, with good tolerability and safety profile in adolescents and adults with asthma currently receiving ICS.
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The effect of platelet-activating factor on the generation of superoxide anion in human eosinophils and neutrophils.
TL;DR: The data indicate that PAF can stimulate leukocyte O2- generation, but this response is greater in the EOS than the neutrophil, and this difference may contribute to participation of PAF in asthma.
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Interferon- γ Enhances Rhinovirus-Induced RANTES Secretion by Airway Epithelial Cells
Shin-Ichi Konno,Kristine Grindle,Wai-Ming Lee,Mary K. Schroth,Anne G. Mosser,Rebecca A. Brockman-Schneider,William W. Busse,James E. Gern +7 more
TL;DR: It is demonstrated that IFN-gamma can enhance rhinovirus-induced RANTES secretion by increasing viral binding, and through a second receptor-independent pathway, to suggest thatIFN-Gamma, by upregulating RantES secretion, could be an important regulator of the initial immune response to rh inovirus infections.
Journal ArticleDOI
Characteristics of perimenstrual asthma and its relation to asthma severity and control: data from the Severe Asthma Research Program.
Chitra K. Rao,Charity G. Moore,Eugene R. Bleecker,William W. Busse,William J. Calhoun,Mario Castro,Kian Fan Chung,Serpil C. Erzurum,Elliot Israel,Douglas Curran-Everett,Sally E. Wenzel +10 more
TL;DR: In this article, the authors identify clinical, demographic, and inflammatory factors associated with perimenstrual asthma and assess the association of PMA with asthma severity and control, using a severity-adjusted model predicting PMA.