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William W. Busse
Researcher at University of Wisconsin-Madison
Publications - 740
Citations - 62685
William W. Busse is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Asthma & Eosinophil. The author has an hindex of 115, co-authored 697 publications receiving 56703 citations. Previous affiliations of William W. Busse include National Institutes of Health & University at Buffalo.
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Journal ArticleDOI
Rhinovirus-induced PBMC responses and outcome of experimental infection in allergic subjects
TL;DR: Findings suggest that variations in mononuclear cell responses to RV could contribute to the individual variability in viral shedding during experimentally induced, and perhaps naturally acquired, RV infections in subjects with respiratory allergy or asthma.
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Alterations of the Arginine Metabolome in Asthma
Abigail R. Lara,Sumita Khatri,Sumita Khatri,Zeneng Wang,Suzy A. A. Comhair,Weiling Xu,Raed A. Dweik,Melanie Bodine,Bruce S. Levison,Jeffrey P. Hammel,Eugene R. Bleecker,William W. Busse,William J. Calhoun,Mario Castro,Fan Chung Kian,Douglas Curran-Everett,Benjamin Gaston,Elliot Israel,Nizar N. Jarjour,Wendy C. Moore,Stephen P. Peters,W. Gerald Teague,Sally E. Wenzel,Stanley A Hazen,Serpil C. Erzurum +24 more
TL;DR: Modeling confirmed that measures of Arg bioavailabilty predict airflow obstruction only in severe asthma, and Unlike Fe(NO), Arg bioavailability is not a surrogate measure of inflammation; however, Arg bio availability is strongly associated with airflow abnormalities insevere asthma.
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Seasonal risk factors for asthma exacerbations among inner-city children.
Stephen J. Teach,Peter J. Gergen,Stanley J. Szefler,Herman Mitchell,Agustin Calatroni,Jeremy Wildfire,Gordon R. Bloomberg,Carolyn M. Kercsmar,Andrew H. Liu,Melanie M. Makhija,Elizabeth C. Matsui,Wayne J. Morgan,George T. O'Connor,William W. Busse +13 more
TL;DR: Among a large cohort of inner-city children with asthma, patients' risk factors for exacerbation vary by season, so information on individual patients might be beneficial in strategies to prevent these seasonal events.
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IL4Rα Mutations Are Associated with Asthma Exacerbations and Mast Cell/IgE Expression
Sally E. Wenzel,Silvana Balzar,Elizabeth J. Ampleford,Gregory A. Hawkins,William W. Busse,William J. Calhoun,Mario Castro,K. Fan Chung,Serpil C. Erzurum,Benjamin Gaston,Elliot Israel,W. Gerald Teague,Douglas Curran-Everett,Deborah A. Meyers,Eugene R. Bleecker +14 more
TL;DR: Allelic substitutions in IL4Rα are associated with asthma exacerbations, lower lung function, and tissue inflammation, in particular to mast cells and IgE.
Journal Article
Eosinophils in asthma.
TL;DR: The eosinophil may be a good target for future therapeutic interventions because of its central role in the pathogenesis of asthma and the fact that it is found in increased numbers in the circulation and sputum in relation to the severity of asthma.