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William W. Busse
Researcher at University of Wisconsin-Madison
Publications - 740
Citations - 62685
William W. Busse is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Asthma & Eosinophil. The author has an hindex of 115, co-authored 697 publications receiving 56703 citations. Previous affiliations of William W. Busse include National Institutes of Health & University at Buffalo.
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Journal ArticleDOI
Baseline FeNO as a prognostic biomarker for subsequent severe asthma exacerbations in patients with uncontrolled, moderate-to-severe asthma receiving placebo in the LIBERTY ASTHMA QUEST study: a post-hoc analysis.
William W. Busse,Sally E. Wenzel,Thomas B. Casale,J. Mark FitzGerald,Megan S. Rice,Nadia Daizadeh,Yamo Deniz,Naimish Patel,Sivan Harel,Paul Rowe,Neil M.H. Graham,Thomas G. O'Riordan,Ian D. Pavord +12 more
TL;DR: In this article, the authors assessed the added prognostic value of baseline fractional exhaled nitric oxide (FeNO) to blood eosinophil count and prior severe asthma exacerbations for subsequent exacerbations.
Journal ArticleDOI
Future Research Directions in Asthma
William W. Busse,Susan Banks-Schlegel,Patricia Noel,Hector Ortega,Virginia S. Taggart,Jack A. Elias +5 more
TL;DR: The priority areas for research in asthma include: innate immunity, adaptive immunity, and tolerance; mechanisms and consequences of persistent asthma and asthma exacerbations; and airway remodeling: clinical consequences and reversibility (clinical relevance and resolutio...
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The presence of hypodense eosinophils and diminished chemiluminescence response in asthma
Peter Shult,Mark Lega,Sharin Jadidi,Rose F. Vrtis,Thomas F. Warner,Frank M. Graziano,William W. Busse +6 more
TL;DR: Differences in eosinophil CL between normal subjects and subjects with asthma did not correlate with the severity of airway obstruction or the peripheral blood eosInophil count, raising the possibility that their presence represents previous eos inophil activation.
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Human airway and peripheral blood eosinophils enhance Th1 and Th2 cytokine secretion
Lin Ying Liu,Sameer K. Mathur,Julie B. Sedgwick,Nizar N. Jarjour,William W. Busse,Elizabeth A. B. Kelly +5 more
TL;DR: Whether human blood and airway eosinophils can contribute to Th1 and Th2 cytokine generation from CD4+ T cells stimulated with superantigen is determined.
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Determinants of Exhaled Breath Condensate pH in a Large Population With Asthma
Lei Liu,W. Gerald Teague,Serpil C. Erzurum,Anne M. Fitzpatrick,Sneha Mantri,Raed A. Dweik,Eugene R. Bleecker,Deborah A. Meyers,William W. Busse,William J. Calhoun,Mario Castro,Kian Fan Chung,Douglas Curran-Everett,Elliot Israel,W. Nizar Jarjour,Wendy C. Moore,Stephen P. Peters,Sally E. Wenzel,John F. Hunt,Benjamin Gaston +19 more
TL;DR: By multiple linear regression, low EBC pH was associated with high BMI, high BAL neutrophil counts, low prebronchodilator FEV(1) ratio, high allergy symptoms, race other than white, and gastroesophageal reflux symptoms.