W
William W. Busse
Researcher at University of Wisconsin-Madison
Publications - 740
Citations - 62685
William W. Busse is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Asthma & Eosinophil. The author has an hindex of 115, co-authored 697 publications receiving 56703 citations. Previous affiliations of William W. Busse include National Institutes of Health & University at Buffalo.
Papers
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Journal ArticleDOI
Baseline asthma burden, comorbidities, and biomarkers in omalizumab-treated patients in PROSPERO
Bradley E. Chipps,Robert S. Zeiger,Allan T. Luskin,William W. Busse,Benjamin Trzaskoma,Evgeniya Antonova,Hooman Pazwash,Susan L. Limb,Paul G. Solari,Noelle M. Griffin,Thomas B. Casale +10 more
TL;DR: The population initiating omalizumab in PROSPERO reported poorly controlled asthma and a substantial disease burden.
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Characterization of granulocyte beta adrenergic receptors in atopic eczema
TL;DR: It was found that 15,000 to 20,000 binding sites of this lower affinity for DHA exist per cell in granulocytes from the two populations of subjects, suggesting that the reduced isoproterenol responsiveness from patients with atopic eczema is not the result of abnormal or reduced numbers of beta-adrenergic receptors.
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Benefits of Airway Androgen Receptor Expression in Human Asthma.
Joe Zein,Joe Zein,Jeffrey M. McManus,Nima Sharifi,Serpil C. Erzurum,Serpil C. Erzurum,Nadzeya Marozkina,Timothy Lahm,Olivia K Giddings,Michael D. Davis,Mark D. DeBoer,Suzy A. A. Comhair,Suzy A. A. Comhair,Peter Bazeley,Peter Bazeley,Hyun Jo Kim,William W. Busse,William J. Calhoun,Mario Castro,Kian Fan Chung,John V. Fahy,John V. Fahy,Elliot Israel,Nizar N. Jarjour,Bruce D. Levy,David T. Mauger,Wendy C. Moore,Victor E. Ortega,Michael C. Peters,Eugene R. Bleecker,Deborah A. Meyers,Yi Zhao,Sally E. Wenzel,Benjamin Gaston +33 more
TL;DR: In this paper, Androgens are potentially beneficial in asthma, but AR (androgen receptor) has not been studied in human airways and its ligands are associated with hum...
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Allergen-induced activation of natural killer cells represents an early-life immune response in the development of allergic asthma
Matthew C. Altman,Matthew C. Altman,Elizabeth Whalen,Alkis Togias,George T. O'Connor,Leonard B. Bacharier,Gordon R. Bloomberg,Meyer Kattan,Robert A. Wood,Scott R. Presnell,Petra LeBeau,Katy F. Jaffee,Cynthia M. Visness,William W. Busse,James E. Gern +14 more
TL;DR: The NK cell–like response was reproducible in an independent group of children with later‐onset allergic sensitization and asthma and was found to be specific to only those children with both aeroallergen sensitized and asthma.
Journal ArticleDOI
Markers of vascular perturbation correlate with airway structural change in asthma
Mats W. Johansson,Stanley J. Kruger,Mark L. Schiebler,Michael D. Evans,Ronald L. Sorkness,Loren C. Denlinger,William W. Busse,Nizar N. Jarjour,Robert R. Montgomery,Deane F. Mosher,Sean B. Fain +10 more
TL;DR: Plasma VWFpp and P-selectin may be useful as surrogates of functional and structural defects that are evident on imaging as well as raising important questions about why these products are associated specifically with different imaging abnormalities.