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William W. Busse

Researcher at University of Wisconsin-Madison

Publications -  740
Citations -  62685

William W. Busse is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Asthma & Eosinophil. The author has an hindex of 115, co-authored 697 publications receiving 56703 citations. Previous affiliations of William W. Busse include National Institutes of Health & University at Buffalo.

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Effect of Bordetella pertussis vaccination in mice and the isolated tracheal response to isoprenaline.

TL;DR: These studies demonstrated that in tracheal smooth muscle isolated from B. pertussis vaccinated mice, the relaxant effects of isoprenaline are impaired.
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Late allergic airway response to segmental bronchopulmonary provocation in allergic subjects is related to peripheral blood basophil histamine release

TL;DR: The data suggest that the intensity of airway eosinophilia in response to antigen challenge is correlated with the magnitude of basophil mediator release in allergic subjects.
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Management of asthma exacerbations

TL;DR: Fitzgerald et al. as discussed by the authors evaluated the effect of doubling the dose of inhaled corticosteroids on patients with asthma exacerbations. But they found that a double dose is not enough for patients who are not responding to β agonist rescue treatment in the usual manner.
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Theophylline Inhibits the Late Asthmatic Response to Nighttime Antigen Challenge in Patients with Mild Atopic Asthma

TL;DR: Nocturnal administration of controlled-release theophylline increases the tolerance to inhaled antigen and reduces severity of LAR, and these data support the possibility of antiinflammatory effects associated with theophyLLine use.
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Global Initiative for Asthma 2016–derived asthma control with fluticasone propionate and salmeterol: A Gaining Optimal Asthma Control (GOAL) study reanalysis

TL;DR: A markedly higher proportion of patients with uncontrolled asthma in each stratum achieved control according to GINA 2016 criteria compared with the original study criteria, and the proportion of Patients achieving control remained greater with fluticasone propionate and salmeterol than with flietasone Propionate alone.