Xiao-Jun Wu

TL;DR: Parts of phero-perception, stress responses, immune function and regulation of gene expression that support the persistence of B. glabrata are described and several potential targets for developing novel control measures aimed at reducing snail-mediated transmission of schistosomiasis are identified.

TL;DR: RNA-interference will enable direct assessment of the roles of individual genes in physiological processes of larval stages of S. mansoni, a crucial step in the identification of novel intervention targets for this important human pathogen.

TL;DR: This study significantly expands the repertoire of LTPs associated with larval transformation and identifies several, e.g., those involved in stress responses, proteolysis/inhibition, antioxidant and detoxication, and immune modulation, that may play a parasite protective role during this crucial period of transition.

TL;DR: In this paper, a cDNA encoding an integrin subunit was cloned and structurally characterized from an embryonic cell line derived from Biomphalaria glabrata, snail intermediate host of the human blood fluke Schistosoma mansoni.

TL;DR: This study is the first to provide a global comparative proteomic analysis of constitutively expressed plasma proteins from susceptible and resistant B. glabrata strains capable of binding early-expressed larval S. mansoni proteins.