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Si-Ming Zhang

Researcher at University of New Mexico

Publications -  45
Citations -  2731

Si-Ming Zhang is an academic researcher from University of New Mexico. The author has contributed to research in topics: Biomphalaria glabrata & Schistosoma mansoni. The author has an hindex of 22, co-authored 36 publications receiving 2429 citations. Previous affiliations of Si-Ming Zhang include Kunming Institute of Zoology.

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Invertebrate immune systems--not homogeneous, not simple, not well understood.

TL;DR: Data suggest that novel immune capabilities will be found among the different invertebrate phyla, and a model is presented that supports the adaptive value of diversified non‐self recognition molecules in invertebrates.
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Diversification of Ig Superfamily Genes in an Invertebrate

TL;DR: It is shown that the IgSF1 domain of the FREP3 subfamily is diversified at the genomic level at higher rates than those recorded for control genes.
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Whole genome analysis of a schistosomiasis-transmitting freshwater snail.

Coen M. Adema, +120 more
TL;DR: Parts of phero-perception, stress responses, immune function and regulation of gene expression that support the persistence of B. glabrata are described and several potential targets for developing novel control measures aimed at reducing snail-mediated transmission of schistosomiasis are identified.
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The primary role of fibrinogen-related proteins in invertebrates is defense, not coagulation.

TL;DR: The range of invertebrate organisms FREPs can be found in, and the roles these molecules play in defense and protection against infection are outlined, with emphasis on specific FReDs called fibrinogen-related proteins (FREPs) identified from the schistosome-transmitting mollusc Biomphalaria glabrata.
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Role for a somatically diversified lectin in resistance of an invertebrate to parasite infection

TL;DR: Knock-down of FREP3 in resistant snails using siRNA-mediated interference resulted in increased susceptibility to E. paraensei, providing a direct link between a gastropod immune molecule and resistance to trematodes.