Y
Yoshifumi Fukunishi
Researcher at National Institute of Advanced Industrial Science and Technology
Publications - 125
Citations - 2675
Yoshifumi Fukunishi is an academic researcher from National Institute of Advanced Industrial Science and Technology. The author has contributed to research in topics: Docking (molecular) & Virtual screening. The author has an hindex of 25, co-authored 120 publications receiving 2454 citations. Previous affiliations of Yoshifumi Fukunishi include Tokyo Metropolitan University & Rutgers University.
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Journal ArticleDOI
Functional annotation of a full-length mouse cDNA collection
Jun Kawai,Akira Shinagawa,K. Shibata,Masayasu Yoshino,Masayoshi Itoh,Y. Ishii,Takahiro Arakawa,A. Hara,Yoshifumi Fukunishi,Hideaki Konno,Jun Adachi,S. Fukuda,Katsunori Aizawa,Masaki Izawa,Kenichiro Nishi,H. Kiyosawa,S. Kondo,Itaru Yamanaka,Takashi Saito,Yasushi Okazaki,Takashi Gojobori,Hidemasa Bono,Takeya Kasukawa,Rintaro Saito,Koji Kadota,Hideo Matsuda,Michael Ashburner,Serge Batalov,Thomas L. Casavant,W. Fleischmann,Terry Gaasterland,Carmela Gissi,Benjamin L. King,Hiromi Kochiwa,P. Kuehl,Simon L. Lewis,Y. Matsuo,Itoshi Nikaido,Graziano Pesole,John Quackenbush,Lynn M. Schriml,F. Staubli,R. Suzuki,Masaru Tomita,Lukas Wagner,Takanori Washio,K. Sakai,Toshihisa Okido,Masaaki Furuno,H. Aono,Richard M. Baldarelli,Gregory S. Barsh,Judith A. Blake,Dario Boffelli,N. Bojunga,Piero Carninci,M. F. De Bonaldo,Michael J. Brownstein,Carol J. Bult,Christopher D.M. Fletcher,Masaki Fujita,Manuela Gariboldi,Stefano Gustincich,David E. Hill,Marion A. Hofmann,David A. Hume,Mamoru Kamiya,Norman H. Lee,Paul A. Lyons,Luigi Marchionni,Jun Mashima,J. Mazzarelli,Peter Mombaerts,P. Nordone,Brian Z. Ring,M. Ringwald,Ivan Rodriguez,Naoaki Sakamoto,H. Sasaki,K. Sato,Christian Schönbach,Tsukasa Seya,Y. Shibata,Kai-Florian Storch,Harukazu Suzuki,Kazuhito Toyo-oka,Kuan Hong Wang,Charles J. Weitz,Charles A. Whittaker,L. Wilming,Anthony Wynshaw-Boris,K. Yoshida,Y. Hasegawa,Hideya Kawaji,Hideya Kawaji,S. Kohtsuki,Yoshihide Hayashizaki +96 more
TL;DR: The first RIKEN clone collection is described, which is one of the largest described for any organism and analysis of these cDNAs extends known gene families and identifies new ones.
Journal ArticleDOI
The Filling Potential Method: A Method for Estimating the Free Energy Surface for Protein−Ligand Docking
TL;DR: The filling potential method as mentioned in this paper is an umbrella potential sampling method, and enables the ligand molecule to drift from its local minima automatically, which is a type of self-avoiding random walk consisting of a cycle of local minimum searches and transition state searches.
Journal ArticleDOI
Protein-Protein Interaction Panel Using Mouse Full-Length cDNAs
Harukazu Suzuki,Yoshifumi Fukunishi,Ikuko Kagawa,Rintaro Saito,Hiroshi Oda,Toshinori Endo,Shinji Kondo,Hidemasa Bono,Yasushi Okazaki,Yoshihide Hayashizaki +9 more
TL;DR: This high-throughput assay system will discover many interactions to facilitate understanding of the function of uncharacterized proteins and the molecular mechanism of crucial biological processes, and also enable completion of a rough draft of the entire PPI panel in certain cell types or tissues of mouse within a short time.
Journal ArticleDOI
Similarities among receptor pockets and among compounds: analysis and application to in silico ligand screening.
TL;DR: A new method to evaluate the distances and similarities between receptor pockets or chemical compounds based on a multi-receptor versus multi-ligand docking affinity matrix was developed, and it was demonstrated that this method achieves a high hit ratio, as compared to that of a uniform sampling.
Journal ArticleDOI
Prediction of Synthetic Accessibility Based on Commercially Available Compound Databases
TL;DR: A new method of predicting SA using commercially available compound databases and molecular descriptors was developed and reproduced the expert manual assessments with a Pearson correlation coefficient of 0.56.